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PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.
Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R. Matsui H, et al. Among authors: takeda s. Hum Mol Genet. 2013 Jun 15;22(12):2423-34. doi: 10.1093/hmg/ddt095. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23449626 Free PMC article.
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.
Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, Takahashi R. Matsui H, et al. Among authors: takeda s. FEBS Lett. 2013 May 2;587(9):1316-25. doi: 10.1016/j.febslet.2013.02.046. Epub 2013 Mar 13. FEBS Lett. 2013. PMID: 23499937 Free article.
Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein.
Uemura N, Koike M, Ansai S, Kinoshita M, Ishikawa-Fujiwara T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R. Uemura N, et al. Among authors: takeda s. PLoS Genet. 2015 Apr 2;11(4):e1005065. doi: 10.1371/journal.pgen.1005065. eCollection 2015 Apr. PLoS Genet. 2015. PMID: 25835295 Free PMC article.
3,760 results