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The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor.
Takahashi T, Huang Y, Yamamoto K, Hamano G, Kakino A, Kang F, Imaizumi Y, Takeshita H, Nozato Y, Nozato S, Yokoyama S, Nagasawa M, Kawai T, Takeda M, Fujimoto T, Hongyo K, Nakagami F, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Gaisano HY, Sawamura T, Rakugi H. Takahashi T, et al. Among authors: takeda m. iScience. 2021 Jan 21;24(2):102076. doi: 10.1016/j.isci.2021.102076. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659870 Free PMC article.
Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.
Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T, Rakugi H. Yamamoto K, et al. Among authors: takeda m. FASEB J. 2015 Aug;29(8):3342-56. doi: 10.1096/fj.15-271627. Epub 2015 Apr 15. FASEB J. 2015. PMID: 25877213
Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice.
Nozato S, Yamamoto K, Takeshita H, Nozato Y, Imaizumi Y, Fujimoto T, Yokoyama S, Nagasawa M, Takeda M, Hongyo K, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Mogi M, Horiuchi M, Rakugi H. Nozato S, et al. Among authors: takeda m. Clin Sci (Lond). 2019 Sep 24;133(18):2005-2018. doi: 10.1042/CS20190573. Print 2019 Sep 30. Clin Sci (Lond). 2019. PMID: 31519791
Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice.
Takeshita H, Yamamoto K, Nozato S, Inagaki T, Tsuchimochi H, Shirai M, Yamamoto R, Imaizumi Y, Hongyo K, Yokoyama S, Takeda M, Oguro R, Takami Y, Itoh N, Takeya Y, Sugimoto K, Fukada SI, Rakugi H. Takeshita H, et al. Among authors: takeda m. Sci Rep. 2017 Feb 8;7:42323. doi: 10.1038/srep42323. Sci Rep. 2017. PMID: 28176863 Free PMC article.
Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice.
Takeshita H, Yamamoto K, Nozato S, Takeda M, Fukada SI, Inagaki T, Tsuchimochi H, Shirai M, Nozato Y, Fujimoto T, Imaizumi Y, Yokoyama S, Nagasawa M, Hamano G, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Takeda S, Takahashi T, Akasaka H, Itoh N, Takami Y, Takeya Y, Sugimoto K, Nakagami H, Rakugi H. Takeshita H, et al. Among authors: takeda m, takeda s. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):975-986. doi: 10.1002/jcsm.12334. Epub 2018 Sep 11. J Cachexia Sarcopenia Muscle. 2018. PMID: 30207087 Free PMC article.
Severity of obstructive sleep apnea is associated with the nocturnal fluctuation of pulse rate, but not with that of blood pressure, in older hypertensive patients receiving calcium channel blockers.
Nozato S, Yamamoto K, Nozato Y, Akasaka H, Hongyo K, Takeda M, Takami Y, Takeya Y, Sugimoto K, Ito N, Rakugi H. Nozato S, et al. Among authors: takeda m. Geriatr Gerontol Int. 2019 Jul;19(7):604-610. doi: 10.1111/ggi.13673. Epub 2019 May 1. Geriatr Gerontol Int. 2019. PMID: 31044515
4,006 results