Takeda K - Search Results

1

Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction.

Mizuta S, Otaki H, Ishikawa T, Makau JN, Yamaguchi T, Fujimoto T, Takakura N, Sakauchi N, Kitamura S, Nono H, Nishi R, Tanaka Y, Takeda K, Nishida N, Watanabe K. Mizuta S, et al. Among authors: takeda k. J Med Chem. 2022 Jan 13;65(1):369-385. doi: 10.1021/acs.jmedchem.1c01527. Epub 2021 Dec 14. J Med Chem. 2022. PMID: 34905383

2

Screening of Inhibitors Targeting Heat Shock Protein 47 Involved in the Development of Idiopathic Pulmonary Fibrosis.

Okuno D, Sakamoto N, Tagod MSO, Akiyama Y, Moriyama S, Miyamura T, Hara A, Kido T, Ishimoto H, Ishimatsu Y, Tanaka T, Ishihara J, Takeda K, Tanaka Y, Mukae H. Okuno D, et al. Among authors: takeda k. ChemMedChem. 2021 Aug 19;16(16):2515-2523. doi: 10.1002/cmdc.202100064. Epub 2021 May 19. ChemMedChem. 2021. PMID: 33890415

3

Marine-derived microbes and molecules for drug discovery.

Tanaka Y, Nishikawa M, Kamisaki K, Hachiya S, Nakamura M, Kuwazuru T, Tanimura S, Soyano K, Takeda K. Tanaka Y, et al. Among authors: takeda k. Inflamm Regen. 2022 Jun 3;42(1):18. doi: 10.1186/s41232-022-00207-9. Inflamm Regen. 2022. PMID: 35655291 Free PMC article. Review.

4

Stress-activated MAP kinase cascades in cellular senescence.

Maruyama J, Naguro I, Takeda K, Ichijo H. Maruyama J, et al. Among authors: takeda k. Curr Med Chem. 2009;16(10):1229-35. doi: 10.2174/092986709787846613. Curr Med Chem. 2009. PMID: 19355881 Review.

5

Identification of novel ASK1 inhibitors using virtual screening.

Okamoto M, Saito N, Kojima H, Okabe T, Takeda K, Ichijo H, Furuya T, Nagano T. Okamoto M, et al. Among authors: takeda k. Bioorg Med Chem. 2011 Jan 1;19(1):486-9. doi: 10.1016/j.bmc.2010.11.004. Epub 2010 Nov 12. Bioorg Med Chem. 2011. PMID: 21134755

6

WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3.

Honda S, Sadatomi D, Yamamura Y, Nakashioya K, Tanimura S, Takeda K. Honda S, et al. Among authors: takeda k. Cancer Sci. 2017 Mar;108(3):520-527. doi: 10.1111/cas.13154. Cancer Sci. 2017. PMID: 28035720 Free PMC article.

7

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.

Okazaki T, Higuchi M, Takeda K, Iwatsuki-Horimoto K, Kiso M, Miyagishi M, Yanai H, Kato A, Yoneyama M, Fujita T, Taniguchi T, Kawaoka Y, Ichijo H, Gotoh Y. Okazaki T, et al. Among authors: takeda k. Sci Signal. 2015 Aug 4;8(388):ra78. doi: 10.1126/scisignal.aab1883. Sci Signal. 2015. PMID: 26243192

8

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.

Sekine S, Kanamaru Y, Koike M, Nishihara A, Okada M, Kinoshita H, Kamiyama M, Maruyama J, Uchiyama Y, Ishihara N, Takeda K, Ichijo H. Sekine S, et al. Among authors: takeda k. J Biol Chem. 2012 Oct 5;287(41):34635-45. doi: 10.1074/jbc.M112.357509. Epub 2012 Aug 22. J Biol Chem. 2012. PMID: 22915595 Free PMC article.

9

Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.

Matsuura H, Nishitoh H, Takeda K, Matsuzawa A, Amagasa T, Ito M, Yoshioka K, Ichijo H. Matsuura H, et al. Among authors: takeda k. J Biol Chem. 2002 Oct 25;277(43):40703-9. doi: 10.1074/jbc.M202004200. Epub 2002 Aug 19. J Biol Chem. 2002. PMID: 12189133 Free article.

10

Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death.

Noguchi T, Takeda K, Matsuzawa A, Saegusa K, Nakano H, Gohda J, Inoue J, Ichijo H. Noguchi T, et al. Among authors: takeda k. J Biol Chem. 2005 Nov 4;280(44):37033-40. doi: 10.1074/jbc.M506771200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129676 Free article.

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