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Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19.
Kawakami E, Saiki N, Yoneyama Y, Moriya C, Maezawa M, Kawamura S, Kinebuchi A, Kono T, Funata M, Sakoda A, Kondo S, Ebihara T, Matsumoto H, Togami Y, Ogura H, Sugihara F, Okuzaki D, Kojima T, Deguchi S, Vallee S, McQuade S, Islam R, Natarajan M, Ishigaki H, Nakayama M, Nguyen CT, Kitagawa Y, Wu Y, Mori K, Hishiki T, Takasaki T, Itoh Y, Takayama K, Nio Y, Takebe T. Kawakami E, et al. Among authors: takayama k. Cell Stem Cell. 2023 Oct 5;30(10):1315-1330.e10. doi: 10.1016/j.stem.2023.09.001. Cell Stem Cell. 2023. PMID: 37802037
Establishment of MDR1-knockout human induced pluripotent stem cell line.
Negoro R, Kawai K, Ichikawa M, Deguchi S, Takayama K, Mizuguchi H. Negoro R, et al. Among authors: takayama k. Drug Metab Pharmacokinet. 2020 Jun;35(3):288-296. doi: 10.1016/j.dmpk.2020.01.009. Epub 2020 Feb 10. Drug Metab Pharmacokinet. 2020. PMID: 32303458
In Vitro and Animal Models for SARS-CoV-2 research.
Takayama K. Takayama K. Trends Pharmacol Sci. 2020 Aug;41(8):513-517. doi: 10.1016/j.tips.2020.05.005. Epub 2020 May 30. Trends Pharmacol Sci. 2020. PMID: 32553545 Free PMC article. Review.
SARS-CoV-2 research using human pluripotent stem cells and organoids.
Deguchi S, Serrano-Aroca Á, Tambuwala MM, Uhal BD, Brufsky AM, Takayama K. Deguchi S, et al. Among authors: takayama k. Stem Cells Transl Med. 2021 Nov;10(11):1491-1499. doi: 10.1002/sctm.21-0183. Epub 2021 Jul 24. Stem Cells Transl Med. 2021. PMID: 34302450 Free PMC article. Review.
Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells.
Hashimoto R, Sakamoto A, Deguchi S, Yi R, Sano E, Hotta A, Takahashi K, Yamanaka S, Takayama K. Hashimoto R, et al. Among authors: takayama k. Mol Ther Nucleic Acids. 2021 Dec 3;26:1107-1114. doi: 10.1016/j.omtn.2021.10.016. Epub 2021 Oct 20. Mol Ther Nucleic Acids. 2021. PMID: 34692233 Free PMC article.
Cell response analysis in SARS-CoV-2 infected bronchial organoids.
Sano E, Suzuki T, Hashimoto R, Itoh Y, Sakamoto A, Sakai Y, Saito A, Okuzaki D, Motooka D, Muramoto Y, Noda T, Takasaki T, Sakuragi JI, Minami S, Kobayashi T, Yamamoto T, Matsumura Y, Nagao M, Okamoto T, Takayama K. Sano E, et al. Among authors: takayama k. Commun Biol. 2022 May 30;5(1):516. doi: 10.1038/s42003-022-03499-2. Commun Biol. 2022. PMID: 35637255 Free PMC article.
2,164 results