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Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition.
Yamasaki T, Hirose H, Yamashita T, Takakura N, Morimoto S, Nakahata T, Kina A, Nakano Y, Okano Tamura Y, Sugama J, Odani T, Shimizu Y, Iwasaki S, Watanabe M, Maekawa T, Kasai S. Yamasaki T, et al. Among authors: takakura n. Bioorg Med Chem. 2017 Aug 1;25(15):4153-4162. doi: 10.1016/j.bmc.2017.06.003. Epub 2017 Jun 13. Bioorg Med Chem. 2017. PMID: 28622905
Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety.
Furukawa H, Miyamoto Y, Hirata Y, Watanabe K, Hitomi Y, Yoshitomi Y, Aida J, Noguchi N, Takakura N, Takami K, Miwatashi S, Hirozane Y, Hamada T, Ito R, Ookawara M, Moritoh Y, Watanabe M, Maekawa T. Furukawa H, et al. Among authors: takakura n. J Med Chem. 2020 Sep 24;63(18):10352-10379. doi: 10.1021/acs.jmedchem.0c00843. Epub 2020 Sep 9. J Med Chem. 2020. PMID: 32900194
Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency.
Yoshida M, Ishioka Y, Ozawa T, Okuyama H, Iguchi M, Ota T, Ito T, Nagira M, Morita A, Tanaka H, Naito H, Kidoya H, Takakura N. Yoshida M, et al. Among authors: takakura n. Sci Rep. 2017 Sep 11;7(1):11137. doi: 10.1038/s41598-017-11605-2. Sci Rep. 2017. PMID: 28894200 Free PMC article.
357 results