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Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID.
Grady CB, Bhattacharjee B, Silva J, Jaycox J, Lee LW, Monteiro VS, Sawano M, Massey D, Caraballo C, Gehlhausen JR, Tabachnikova A, Mao T, Lucas C, Peña-Hernandez MA, Xu L, Tzeng TJ, Takahashi T, Herrin J, Güthe DB, Akrami A, Assaf G, Davis H, Harris K, McCorkell L, Schulz WL, Grffin D, Wei H, Ring AM, Guan L, Cruz CD, Iwasaki A, Krumholz HM. Grady CB, et al. Among authors: takahashi t. medRxiv [Preprint]. 2024 Jan 12:2024.01.11.24300929. doi: 10.1101/2024.01.11.24300929. medRxiv. 2024. PMID: 38260484 Free PMC article. Preprint.
Sex differences in immune responses to SARS-CoV-2 that underlie disease outcomes.
Takahashi T, Wong P, Ellingson MK, Lucas C, Klein J, Israelow B, Silva J, Oh JE, Mao T, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Casanovas-Massana A, Cruz CD, Fournier JB, Odio CD, Farhadian S, Grubaugh ND, Schulz WL, Ko AI, Ring AM, Omer SB, Iwasaki A; Yale IMPACT research team. Takahashi T, et al. medRxiv [Preprint]. 2020 Jun 26:2020.06.06.20123414. doi: 10.1101/2020.06.06.20123414. medRxiv. 2020. PMID: 32577695 Free PMC article. Updated. Preprint.
Sex differences in immune responses that underlie COVID-19 disease outcomes.
Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Casanovas-Massana A, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ; Yale IMPACT Research Team; Shaw A, Fournier JB, Odio CD, Farhadian S, Dela Cruz C, Grubaugh ND, Schulz WL, Ring AM, Ko AI, Omer SB, Iwasaki A. Takahashi T, et al. Nature. 2020 Dec;588(7837):315-320. doi: 10.1038/s41586-020-2700-3. Epub 2020 Aug 26. Nature. 2020. PMID: 32846427 Free PMC article.
Kynurenic acid underlies sex-specific immune responses to COVID-19.
Cai Y, Kim DJ, Takahashi T, Broadhurst DI, Ma S, Rattray NJW, Casanovas-Massana A, Israelow B, Klein J, Lucas C, Mao T, Moore AJ, Muenker MC, Oh J, Silva J, Wong P; Yale IMPACT Research team; Ko AI, Khan SA, Iwasaki A, Johnson CH. Cai Y, et al. Among authors: takahashi t. medRxiv [Preprint]. 2020 Sep 8:2020.09.06.20189159. doi: 10.1101/2020.09.06.20189159. medRxiv. 2020. PMID: 32935119 Free PMC article. Updated. Preprint.
Sex differences in immune responses.
Takahashi T, Iwasaki A. Takahashi T, et al. Science. 2021 Jan 22;371(6527):347-348. doi: 10.1126/science.abe7199. Science. 2021. PMID: 33479140 No abstract available.
Kynurenic acid may underlie sex-specific immune responses to COVID-19.
Cai Y, Kim DJ, Takahashi T, Broadhurst DI, Yan H, Ma S, Rattray NJW, Casanovas-Massana A, Israelow B, Klein J, Lucas C, Mao T, Moore AJ, Muenker MC, Oh JE, Silva J, Wong P; Yale IMPACT Research team; Ko AI, Khan SA, Iwasaki A, Johnson CH. Cai Y, et al. Among authors: takahashi t. Sci Signal. 2021 Jul 6;14(690):eabf8483. doi: 10.1126/scisignal.abf8483. Sci Signal. 2021. PMID: 34230210 Free PMC article.
Reply to: A finding of sex similarities rather than differences in COVID-19 outcomes.
Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Casanovas-Massana A, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Shaw A, Fournier JB, Odio CD, Farhadian S, Dela Cruz C, Grubaugh ND, Schulz WL, Ring AM, Ko AI, Omer SB, Iwasaki A. Takahashi T, et al. Nature. 2021 Sep;597(7877):E10-E11. doi: 10.1038/s41586-021-03645-6. Nature. 2021. PMID: 34552250 No abstract available.
Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain.
Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, Yalçın B, Taylor KR, Dutton S, Acosta-Alvarez L, Ni L, Contreras-Esquivel D, Gehlhausen JR, Klein J, Lucas C, Mao T, Silva J, Peña-Hernández MA, Tabachnikova A, Takahashi T, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Hefti M, Perl D, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M. Fernández-Castañeda A, et al. Among authors: takahashi t. bioRxiv [Preprint]. 2022 Jan 10:2022.01.07.475453. doi: 10.1101/2022.01.07.475453. bioRxiv. 2022. PMID: 35043113 Free PMC article. Preprint.
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation.
Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M. Fernández-Castañeda A, et al. Among authors: takahashi t. Cell. 2022 Jul 7;185(14):2452-2468.e16. doi: 10.1016/j.cell.2022.06.008. Epub 2022 Jun 13. Cell. 2022. PMID: 35768006 Free PMC article.
Distinguishing features of Long COVID identified through immune profiling.
Klein J, Wood J, Jaycox J, Lu P, Dhodapkar RM, Gehlhausen JR, Tabachnikova A, Tabacof L, Malik AA, Kamath K, Greene K, Monteiro VS, Peña-Hernandez M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Silva J, Mccarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng TJ, Xu L, Yildirim I, Krumholz HM, Shon J, Medzhitov R, Omer SB, van Dijk D, Ring AM, Putrino D, Iwasaki A. Klein J, et al. Among authors: takahashi t. medRxiv [Preprint]. 2022 Aug 10:2022.08.09.22278592. doi: 10.1101/2022.08.09.22278592. medRxiv. 2022. PMID: 35982667 Free PMC article. Updated. Preprint.
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