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Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events.
Takahashi T, Al-Kofahi M, Jaber M, Bratrude B, Betz K, Suessmuth Y, Yu A, Neuberg DS, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Blazar BR, Horan JT, Watkins B, Langston A, Qayed M, Kean LS. Takahashi T, et al. Blood. 2023 Aug 24;142(8):700-710. doi: 10.1182/blood.2023020035. Blood. 2023. PMID: 37319437 Clinical Trial.
Comparison of Dose Adjustment Strategies for Obesity in High-dose Cyclophosphamide Among Adult Hematopoietic Cell Transplantation Recipients: Pharmacokinetic Analysis.
Takahashi T, Jaber MM, Al-Kofahi M, Weisdorf D, Brunstein C, Bachanova V, Brundage RC, Jacobson PA, Kirstein MN. Takahashi T, et al. Transplant Cell Ther. 2022 Dec;28(12):845.e1-845.e8. doi: 10.1016/j.jtct.2022.09.011. Epub 2022 Sep 24. Transplant Cell Ther. 2022. PMID: 36167308 Free article.
Individualized rabbit anti-thymocyte globulin dosing in adult haploidentical hematopoietic cell transplantation with high-risk hematologic malignancy: Exposure-response analysis and population pharmacokinetics simulations.
Teramoto M, Takahashi T, Matsumoto K, Jaber M, Kaida K, Tamaki H, Ikegame K, Yoshihara S. Teramoto M, et al. Among authors: takahashi t. Am J Hematol. 2024 Mar;99(3):387-395. doi: 10.1002/ajh.27195. Epub 2024 Jan 2. Am J Hematol. 2024. PMID: 38165019
The Adverse Event Landscape of Stem Cell Transplant: Evidence for aGVHD Driving Early Transplant Associated Toxicities.
Takahashi T, Watkins B, Bratrude B, Neuberg D, Hebert K, Betz K, Yu A, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Blazar BR, Horan JT, Langston A, Kean LS, Qayed M. Takahashi T, et al. Transplant Cell Ther. 2024 Apr 6:S2666-6367(24)00317-8. doi: 10.1016/j.jtct.2024.03.030. Online ahead of print. Transplant Cell Ther. 2024. PMID: 38583802
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