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RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane.
Yokoyama S, Kawai T, Yamamoto K, Yibin H, Yamamoto H, Kakino A, Takeshita H, Nozato Y, Fujimoto T, Hongyo K, Takahashi T, Nakagami F, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Sawamura T, Rakugi H. Yokoyama S, et al. Among authors: takahashi t. Sci Rep. 2021 Mar 11;11(1):5759. doi: 10.1038/s41598-021-85312-4. Sci Rep. 2021. PMID: 33707701 Free PMC article.
Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice.
Takeshita H, Yamamoto K, Nozato S, Takeda M, Fukada SI, Inagaki T, Tsuchimochi H, Shirai M, Nozato Y, Fujimoto T, Imaizumi Y, Yokoyama S, Nagasawa M, Hamano G, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Takeda S, Takahashi T, Akasaka H, Itoh N, Takami Y, Takeya Y, Sugimoto K, Nakagami H, Rakugi H. Takeshita H, et al. Among authors: takahashi t. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):975-986. doi: 10.1002/jcsm.12334. Epub 2018 Sep 11. J Cachexia Sarcopenia Muscle. 2018. PMID: 30207087 Free PMC article.
Overexpression of Interleukin-15 exhibits improved glucose tolerance and promotes GLUT4 translocation via AMP-Activated protein kinase pathway in skeletal muscle.
Fujimoto T, Sugimoto K, Takahashi T, Yasunobe Y, Xie K, Tanaka M, Ohnishi Y, Yoshida S, Kurinami H, Akasaka H, Takami Y, Takeya Y, Yamamoto K, Rakugi H. Fujimoto T, et al. Among authors: takahashi t. Biochem Biophys Res Commun. 2019 Feb 19;509(4):994-1000. doi: 10.1016/j.bbrc.2019.01.024. Epub 2019 Jan 14. Biochem Biophys Res Commun. 2019. PMID: 30654941
Preventive effects of low-intensity exercise on cancer cachexia-induced muscle atrophy.
Tanaka M, Sugimoto K, Fujimoto T, Xie K, Takahashi T, Akasaka H, Kurinami H, Yasunobe Y, Matsumoto T, Fujino H, Rakugi H. Tanaka M, et al. Among authors: takahashi t. FASEB J. 2019 Jul;33(7):7852-7862. doi: 10.1096/fj.201802430R. Epub 2019 Mar 27. FASEB J. 2019. PMID: 30916585
These results suggest that low-intensity exercise has the potential to become an effective therapeutic intervention for the prevention of cancer cachexia-induced muscle atrophy.-Tanaka, M., Sugimoto, K., Fujimoto, T., Xie, K., Takahashi, T., Akasaka, H., Kuri …
These results suggest that low-intensity exercise has the potential to become an effective therapeutic intervention for the prevention of ca …
The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor.
Takahashi T, Huang Y, Yamamoto K, Hamano G, Kakino A, Kang F, Imaizumi Y, Takeshita H, Nozato Y, Nozato S, Yokoyama S, Nagasawa M, Kawai T, Takeda M, Fujimoto T, Hongyo K, Nakagami F, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Gaisano HY, Sawamura T, Rakugi H. Takahashi T, et al. iScience. 2021 Jan 21;24(2):102076. doi: 10.1016/j.isci.2021.102076. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659870 Free PMC article.
Effects of luseogliflozin treatment on hyperglycemia-induced muscle atrophy in rats.
Xie K, Sugimoto K, Tanaka M, Akasaka H, Fujimoto T, Takahashi T, Onishi Y, Minami T, Yoshida S, Takami Y, Yamamoto K, Rakugi H. Xie K, et al. Among authors: takahashi t. J Clin Biochem Nutr. 2023 May;72(3):248-255. doi: 10.3164/jcbn.22-58. Epub 2023 Feb 21. J Clin Biochem Nutr. 2023. PMID: 37251965 Free PMC article.
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