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Melatonin is a potential drug for the prevention of bone loss during space flight.
Ikegame M, Hattori A, Tabata MJ, Kitamura KI, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda K, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N. Ikegame M, et al. Among authors: takahashi a. J Pineal Res. 2019 Oct;67(3):e12594. doi: 10.1111/jpi.12594. Epub 2019 Jul 19. J Pineal Res. 2019. PMID: 31286565 Free PMC article.
p53-dependent adaptive responses in human cells exposed to space radiations.
Takahashi A, Su X, Suzuki H, Omori K, Seki M, Hashizume T, Shimazu T, Ishioka N, Iwasaki T, Ohnishi T. Takahashi A, et al. Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1171-6. doi: 10.1016/j.ijrobp.2010.04.062. Epub 2010 Aug 21. Int J Radiat Oncol Biol Phys. 2010. PMID: 20729005
Frozen human cells can record radiation damage accumulated during space flight: mutation induction and radioadaptation.
Yatagai F, Honma M, Takahashi A, Omori K, Suzuki H, Shimazu T, Seki M, Hashizume T, Ukai A, Sugasawa K, Abe T, Dohmae N, Enomoto S, Ohnishi T, Gordon A, Ishioka N. Yatagai F, et al. Among authors: takahashi a. Radiat Environ Biophys. 2011 Mar;50(1):125-34. doi: 10.1007/s00411-010-0348-3. Epub 2010 Dec 14. Radiat Environ Biophys. 2011. PMID: 21161544
Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin use and regulation as a countermeasure.
Hirayama J, Hattori A, Takahashi A, Furusawa Y, Tabuchi Y, Shibata M, Nagamatsu A, Yano S, Maruyama Y, Matsubara H, Sekiguchi T, Suzuki N. Hirayama J, et al. Among authors: takahashi a. J Pineal Res. 2023 Jan;74(1):e12834. doi: 10.1111/jpi.12834. Epub 2022 Oct 17. J Pineal Res. 2023. PMID: 36203395 Review.
Space Radiation Biology for "Living in Space".
Furukawa S, Nagamatsu A, Nenoi M, Fujimori A, Kakinuma S, Katsube T, Wang B, Tsuruoka C, Shirai T, Nakamura AJ, Sakaue-Sawano A, Miyawaki A, Harada H, Kobayashi M, Kobayashi J, Kunieda T, Funayama T, Suzuki M, Miyamoto T, Hidema J, Yoshida Y, Takahashi A. Furukawa S, et al. Among authors: takahashi a. Biomed Res Int. 2020 Apr 8;2020:4703286. doi: 10.1155/2020/4703286. eCollection 2020. Biomed Res Int. 2020. PMID: 32337251 Free PMC article. Review.
4,824 results