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Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex.
Shirai T, Nakai A, Ando E, Fujimoto J, Leach S, Arimori T, Higo D, van Eerden FJ, Tulyeu J, Liu YC, Okuzaki D, Murayama MA, Miyata H, Nunomura K, Lin B, Tani A, Kumanogoh A, Ikawa M, Wing JB, Standley DM, Takagi J, Suzuki K. Shirai T, et al. Among authors: takagi j. Sci Immunol. 2023 Mar 31;8(81):eadc9324. doi: 10.1126/sciimmunol.adc9324. Epub 2023 Mar 31. Sci Immunol. 2023. PMID: 37000855
Structural basis for semaphorin signalling through the plexin receptor.
Nogi T, Yasui N, Mihara E, Matsunaga Y, Noda M, Yamashita N, Toyofuku T, Uchiyama S, Goshima Y, Kumanogoh A, Takagi J. Nogi T, et al. Among authors: takagi j. Nature. 2010 Oct 28;467(7319):1123-7. doi: 10.1038/nature09473. Epub 2010 Sep 29. Nature. 2010. PMID: 20881961
A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.
Nojima S, Toyofuku T, Kamao H, Ishigami C, Kaneko J, Okuno T, Takamatsu H, Ito D, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Ogata A, Ikawa M, Morii E, Aozasa K, Takagi J, Takahashi M, Kumanogoh A. Nojima S, et al. Among authors: takagi j. Nat Commun. 2013;4:1406. doi: 10.1038/ncomms2420. Nat Commun. 2013. PMID: 23360997 Free PMC article.
Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.
Suzuki K, Tsunoda H, Omiya R, Matoba K, Baba T, Suzuki S, Segawa H, Kumanogoh A, Iwasaki K, Hattori K, Takagi J. Suzuki K, et al. Among authors: takagi j. PLoS One. 2016 Jun 3;11(6):e0156719. doi: 10.1371/journal.pone.0156719. eCollection 2016. PLoS One. 2016. PMID: 27258772 Free PMC article.
Mechanistic basis for the recognition of laminin-511 by α6β1 integrin.
Takizawa M, Arimori T, Taniguchi Y, Kitago Y, Yamashita E, Takagi J, Sekiguchi K. Takizawa M, et al. Among authors: takagi j. Sci Adv. 2017 Sep 1;3(9):e1701497. doi: 10.1126/sciadv.1701497. eCollection 2017 Sep. Sci Adv. 2017. PMID: 28879238 Free PMC article.
347 results