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New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Casanova M, Franetich JF, Tajeri S, Malzert-Fréon A, Corvaisier S, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: tajeri s. Eur J Med Chem. 2023 Mar 5;249:115115. doi: 10.1016/j.ejmech.2023.115115. Epub 2023 Jan 13. Eur J Med Chem. 2023. PMID: 36680984
Chloroquine Potentiates Primaquine Activity against Active and Latent Hepatic Plasmodia Ex Vivo: Potentials and Pitfalls.
Dembélé L, Franetich JF, Soulard V, Amanzougaghene N, Tajeri S, Bousema T, van Gemert GJ, Le Grand R, Dereuddre-Bosquet N, Baird JK, Mazier D, Snounou G. Dembélé L, et al. Among authors: tajeri s. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01416-20. doi: 10.1128/AAC.01416-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33077656 Free PMC article.
The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes.
Amanzougaghene N, Tajeri S, Yalaoui S, Lorthiois A, Soulard V, Gego A, Rametti A, Risco-Castillo V, Moreno A, Tefit M, van Gemert GJ, Sauerwein RW, Vaillant JC, Ravassard P, Pérignon JL, Froissard P, Mazier D, Franetich JF. Amanzougaghene N, et al. Among authors: tajeri s. Front Cell Infect Microbiol. 2021 Jun 29;11:704662. doi: 10.3389/fcimb.2021.704662. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34268141 Free PMC article.
2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum.
Amrane D, Arnold CS, Hutter S, Sanz-Serrano J, Collia M, Azqueta A, Paloque L, Cohen A, Amanzougaghene N, Tajeri S, Franetich JF, Mazier D, Benoit-Vical F, Verhaeghe P, Azas N, Vanelle P, Botté C, Primas N. Amrane D, et al. Among authors: tajeri s. Pharmaceuticals (Basel). 2021 Jul 26;14(8):724. doi: 10.3390/ph14080724. Pharmaceuticals (Basel). 2021. PMID: 34451821 Free PMC article.
A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
Bosson-Vanga H, Primas N, Franetich JF, Lavazec C, Gomez L, Ashraf K, Tefit M, Soulard V, Dereuddre-Bosquet N, Le Grand R, Donnette M, Mustière R, Amanzougaghene N, Tajeri S, Suzanne P, Malzert-Fréon A, Rault S, Vanelle P, Hutter S, Cohen A, Snounou G, Roques P, Azas N, Lagardère P, Lisowski V, Masurier N, Nguyen M, Paloque L, Benoit-Vical F, Verhaeghe P, Mazier D. Bosson-Vanga H, et al. Among authors: tajeri s. Microbiol Spectr. 2021 Oct 31;9(2):e0027421. doi: 10.1128/Spectrum.00274-21. Epub 2021 Sep 29. Microbiol Spectr. 2021. PMID: 34724729 Free PMC article.
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