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Secretin activates brown fat and induces satiation.
Laurila S, Sun L, Lahesmaa M, Schnabl K, Laitinen K, Klén R, Li Y, Balaz M, Wolfrum C, Steiger K, Niemi T, Taittonen M, U-Din M, Välikangas T, Elo LL, Eskola O, Kirjavainen AK, Nummenmaa L, Virtanen KA, Klingenspor M, Nuutila P. Laurila S, et al. Among authors: taittonen m. Nat Metab. 2021 Jun;3(6):798-809. doi: 10.1038/s42255-021-00409-4. Epub 2021 Jun 21. Nat Metab. 2021. PMID: 34158656
Functional brown adipose tissue in healthy adults.
Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, Taittonen M, Laine J, Savisto NJ, Enerbäck S, Nuutila P. Virtanen KA, et al. Among authors: taittonen m. N Engl J Med. 2009 Apr 9;360(15):1518-25. doi: 10.1056/NEJMoa0808949. N Engl J Med. 2009. PMID: 19357407 Free article. Clinical Trial.
Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults.
Viljanen AP, Karmi A, Borra R, Pärkkä JP, Lepomäki V, Parkkola R, Lautamäki R, Järvisalo M, Taittonen M, Rönnemaa T, Iozzo P, Knuuti J, Nuutila P, Raitakari OT. Viljanen AP, et al. Among authors: taittonen m. Am J Cardiol. 2009 Jun 15;103(12):1721-6. doi: 10.1016/j.amjcard.2009.02.025. Epub 2009 Apr 16. Am J Cardiol. 2009. PMID: 19539082
Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities.
Bucci M, Borra R, Någren K, Maggio R, Tuunanen H, Oikonen V, Del Ry S, Viljanen T, Taittonen M, Rigazio S, Giannessi D, Parkkola R, Knuuti J, Nuutila P, Iozzo P. Bucci M, et al. Among authors: taittonen m. Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E105-12. doi: 10.1152/ajpendo.00680.2010. Epub 2011 Apr 19. Am J Physiol Endocrinol Metab. 2011. PMID: 21505146 Free article. Clinical Trial.
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans.
Bucci M, Borra R, Någren K, Pärkkä JP, Del Ry S, Maggio R, Tuunanen H, Viljanen T, Cabiati M, Rigazio S, Taittonen M, Pagotto U, Parkkola R, Opie LH, Nuutila P, Knuuti J, Iozzo P. Bucci M, et al. Among authors: taittonen m. Cardiovasc Ther. 2012 Dec;30(6):333-41. doi: 10.1111/j.1755-5922.2011.00275.x. Epub 2011 Jul 31. Cardiovasc Ther. 2012. PMID: 21884010 Free article.
33 results