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Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: tait swg. Nature. 2023 Oct;622(7983):627-636. doi: 10.1038/s41586-023-06621-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821702 Free PMC article.
Mito-priming as a method to engineer Bcl-2 addiction.
Lopez J, Bessou M, Riley JS, Giampazolias E, Todt F, Rochegüe T, Oberst A, Green DR, Edlich F, Ichim G, Tait SW. Lopez J, et al. Nat Commun. 2016 Feb 2;7:10538. doi: 10.1038/ncomms10538. Nat Commun. 2016. PMID: 26833356 Free PMC article.
Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert ML, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SWG. Giampazolias E, et al. Among authors: tait swg. Nat Cell Biol. 2017 Sep;19(9):1116-1129. doi: 10.1038/ncb3596. Epub 2017 Aug 28. Nat Cell Biol. 2017. PMID: 28846096 Free PMC article.
Mitochondria as multifaceted regulators of cell death.
Bock FJ, Tait SWG. Bock FJ, et al. Among authors: tait swg. Nat Rev Mol Cell Biol. 2020 Feb;21(2):85-100. doi: 10.1038/s41580-019-0173-8. Epub 2019 Oct 21. Nat Rev Mol Cell Biol. 2020. PMID: 31636403 Review.
Mitochondrial DNA in inflammation and immunity.
Riley JS, Tait SW. Riley JS, et al. EMBO Rep. 2020 Apr 3;21(4):e49799. doi: 10.15252/embr.201949799. Epub 2020 Mar 23. EMBO Rep. 2020. PMID: 32202065 Free PMC article. Review.
103 results