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Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain.
Tansley S, Uttam S, Ureña Guzmán A, Yaqubi M, Pacis A, Parisien M, Deamond H, Wong C, Rabau O, Brown N, Haglund L, Ouellet J, Santaguida C, Ribeiro-da-Silva A, Tahmasebi S, Prager-Khoutorsky M, Ragoussis J, Zhang J, Salter MW, Diatchenko L, Healy LM, Mogil JS, Khoutorsky A. Tansley S, et al. Among authors: tahmasebi s. Nat Commun. 2022 Feb 11;13(1):843. doi: 10.1038/s41467-022-28473-8. Nat Commun. 2022. PMID: 35149686 Free PMC article.
Multifaceted regulation of somatic cell reprogramming by mRNA translational control.
Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, Sonenberg N. Tahmasebi S, et al. Cell Stem Cell. 2014 May 1;14(5):606-16. doi: 10.1016/j.stem.2014.02.005. Epub 2014 Mar 13. Cell Stem Cell. 2014. PMID: 24630793 Free article.
eIF2α phosphorylation controls thermal nociception.
Khoutorsky A, Sorge RE, Prager-Khoutorsky M, Pawlowski SA, Longo G, Jafarnejad SM, Tahmasebi S, Martin LJ, Pitcher MH, Gkogkas CG, Sharif-Naeini R, Ribeiro-da-Silva A, Bourque CW, Cervero F, Mogil JS, Sonenberg N. Khoutorsky A, et al. Among authors: tahmasebi s. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11949-11954. doi: 10.1073/pnas.1614047113. Epub 2016 Oct 3. Proc Natl Acad Sci U S A. 2016. PMID: 27698114 Free PMC article.
Translation deregulation in human disease.
Tahmasebi S, Khoutorsky A, Mathews MB, Sonenberg N. Tahmasebi S, et al. Nat Rev Mol Cell Biol. 2018 Dec;19(12):791-807. doi: 10.1038/s41580-018-0034-x. Nat Rev Mol Cell Biol. 2018. PMID: 30038383 Review.
4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold.
Sharma V, Sood R, Lou D, Hung TY, Lévesque M, Han Y, Levett JY, Wang P, Murthy S, Tansley S, Wang S, Siddiqui N, Tahmasebi S, Rosenblum K, Avoli M, Lacaille JC, Sonenberg N, Khoutorsky A. Sharma V, et al. Among authors: tahmasebi s. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2025522118. doi: 10.1073/pnas.2025522118. Proc Natl Acad Sci U S A. 2021. PMID: 33876772 Free PMC article.
4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors.
Hooshmandi M, Truong VT, Fields E, Thomas RE, Wong C, Sharma V, Gantois I, Soriano Roque P, Chalkiadaki K, Wu N, Chakraborty A, Tahmasebi S, Prager-Khoutorsky M, Sonenberg N, Suvrathan A, Watt AJ, Gkogkas CG, Khoutorsky A. Hooshmandi M, et al. Among authors: tahmasebi s. Cell Rep. 2021 Apr 27;35(4):109036. doi: 10.1016/j.celrep.2021.109036. Cell Rep. 2021. PMID: 33910008 Free article.
Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1.
Roque PS, Hooshmandi M, Neagu-Lund L, Yin S, Yousefpour N, Sato H, Sato T, Nakadate Y, Kawakami A, Tahmasebi S, Ribeiro-da-Silva A, Gkogkas CG, Prager-Khoutorsky M, Schricker T, Wykes L, Khoutorsky A. Roque PS, et al. Among authors: tahmasebi s. Sci Rep. 2021 Jul 29;11(1):15490. doi: 10.1038/s41598-021-94849-3. Sci Rep. 2021. PMID: 34326413 Free PMC article.
The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).
Farooq Z, Kusuma F, Burke P, Dufour CR, Lee D, Tabatabaei N, Toboz P, Radovani E, Greenblatt JF, Rehman J, Class J, Khoutorsky A, Fonseca BD, Richner JM, Mercier E, Bourque G, Giguère V, Subramaniam AR, Han J, Tahmasebi S. Farooq Z, et al. Among authors: tahmasebi s. J Biol Chem. 2022 Sep;298(9):102277. doi: 10.1016/j.jbc.2022.102277. Epub 2022 Jul 19. J Biol Chem. 2022. PMID: 35863436 Free PMC article.
Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.
Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, Bourque G, Yang XJ, Tian B, Stunnenberg HG, Yamanaka Y, Blencowe BJ, Giguère V, Sonenberg N. Tahmasebi S, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12360-12367. doi: 10.1073/pnas.1615540113. Epub 2016 Oct 24. Proc Natl Acad Sci U S A. 2016. PMID: 27791185 Free PMC article.
The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.
Toboz P, Amiri M, Tabatabaei N, Dufour CR, Kim SH, Fillebeen C, Ayemoba CE, Khoutorsky A, Nairz M, Shao L, Pajcini KV, Kim KW, Giguère V, Oliveira RL, Constante M, Santos MM, Morales CR, Pantopoulos K, Sonenberg N, Pinho S, Tahmasebi S. Toboz P, et al. Among authors: tahmasebi s. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2121251119. doi: 10.1073/pnas.2121251119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994670 Free PMC article.
175 results