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54 results

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Page 1
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C. Kleinberger G, et al. Among authors: tahirovic s. Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093. Sci Transl Med. 2014. PMID: 24990881
Loss of fused in sarcoma (FUS) promotes pathological Tau splicing.
Orozco D, Tahirovic S, Rentzsch K, Schwenk BM, Haass C, Edbauer D. Orozco D, et al. Among authors: tahirovic s. EMBO Rep. 2012 Aug;13(8):759-64. doi: 10.1038/embor.2012.90. Epub 2012 Jun 19. EMBO Rep. 2012. PMID: 22710833 Free PMC article.
Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling.
Fleck D, van Bebber F, Colombo A, Galante C, Schwenk BM, Rabe L, Hampel H, Novak B, Kremmer E, Tahirovic S, Edbauer D, Lichtenthaler SF, Schmid B, Willem M, Haass C. Fleck D, et al. Among authors: tahirovic s. J Neurosci. 2013 May 1;33(18):7856-69. doi: 10.1523/JNEUROSCI.3372-12.2013. J Neurosci. 2013. PMID: 23637177 Free PMC article.
The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes.
Schwenk BM, Lang CM, Hogl S, Tahirovic S, Orozco D, Rentzsch K, Lichtenthaler SF, Hoogenraad CC, Capell A, Haass C, Edbauer D. Schwenk BM, et al. Among authors: tahirovic s. EMBO J. 2014 Mar 3;33(5):450-67. doi: 10.1002/embj.201385857. Epub 2013 Dec 19. EMBO J. 2014. PMID: 24357581 Free PMC article.
Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis.
Götzl JK, Mori K, Damme M, Fellerer K, Tahirovic S, Kleinberger G, Janssens J, van der Zee J, Lang CM, Kremmer E, Martin JJ, Engelborghs S, Kretzschmar HA, Arzberger T, Van Broeckhoven C, Haass C, Capell A. Götzl JK, et al. Among authors: tahirovic s. Acta Neuropathol. 2014;127(6):845-60. doi: 10.1007/s00401-014-1262-6. Epub 2014 Mar 12. Acta Neuropathol. 2014. PMID: 24619111
Inhibition of amyloid-β plaque formation by α-synuclein.
Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, Abou-Ajram C, Nuscher B, Serrano-Pozo A, Müller A, Prinz M, Steiner H, Hyman BT, Haass C, Meyer-Luehmann M. Bachhuber T, et al. Among authors: tahirovic s. Nat Med. 2015 Jul;21(7):802-7. doi: 10.1038/nm.3885. Epub 2015 Jun 22. Nat Med. 2015. PMID: 26099047
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. Willem M, et al. Among authors: tahirovic s. Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864. Epub 2015 Aug 31. Nature. 2015. PMID: 26322584 Free PMC article.
Young microglia restore amyloid plaque clearance of aged microglia.
Daria A, Colombo A, Llovera G, Hampel H, Willem M, Liesz A, Haass C, Tahirovic S. Daria A, et al. Among authors: tahirovic s. EMBO J. 2017 Mar 1;36(5):583-603. doi: 10.15252/embj.201694591. Epub 2016 Dec 21. EMBO J. 2017. PMID: 28007893 Free PMC article.
54 results