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New antimalarial and cytotoxic 4-nerolidylcatechol derivatives.
Pinto AC, Silva LF, Cavalcanti BC, Melo MR, Chaves FC, Lotufo LV, de Moraes MO, de Andrade-Neto VF, Tadei WP, Pessoa CO, Vieira PP, Pohlit AM. Pinto AC, et al. Among authors: tadei wp. Eur J Med Chem. 2009 Jun;44(6):2731-5. doi: 10.1016/j.ejmech.2008.10.025. Epub 2008 Oct 31. Eur J Med Chem. 2009. PMID: 19084293
Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae).
Silva EC, Cavalcanti BC, Amorim RC, Lucena JF, Quadros DS, Tadei WP, Montenegro RC, Costa-Lotufo LV, Pessoa C, Moraes MO, Nunomura RC, Nunomura SM, Melo MR, Andrade-Neto VF, Silva LF, Vieira PP, Pohlit AM. Silva EC, et al. Among authors: tadei wp. Mem Inst Oswaldo Cruz. 2009 Feb;104(1):48-56. doi: 10.1590/s0074-02762009000100008. Mem Inst Oswaldo Cruz. 2009. PMID: 19274376 Free article.
Piper peltatum: biomass and 4-nerolidylcatechol production.
Pinto AC, Chaves FC, dos Santos PA, Nunez CV, Tadei WP, Pohlit AM. Pinto AC, et al. Among authors: tadei wp. Planta Med. 2010 Sep;76(13):1473-6. doi: 10.1055/s-0029-1240938. Epub 2010 Mar 1. Planta Med. 2010. PMID: 20195961
In vivo and in vitro antimalarial activity of 4-nerolidylcatechol.
Rocha E Silva LF, Silva Pinto AC, Pohlit AM, Quignard EL, Vieira PP, Tadei WP, Chaves FC, Samonek JF, Lima CA, Costa MR, Alecrim Md, Andrade-Neto VF. Rocha E Silva LF, et al. Among authors: tadei wp. Phytother Res. 2011 Aug;25(8):1181-8. doi: 10.1002/ptr.3424. Epub 2011 Feb 8. Phytother Res. 2011. PMID: 21302338
Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.
Rocha e Silva LF, Montoia A, Amorim RC, Melo MR, Henrique MC, Nunomura SM, Costa MR, Andrade Neto VF, Costa DS, Dantas G, Lavrado J, Moreira R, Paulo A, Pinto AC, Tadei WP, Zacardi RS, Eberlin MN, Pohlit AM. Rocha e Silva LF, et al. Among authors: tadei wp. Phytomedicine. 2012 Dec 15;20(1):71-6. doi: 10.1016/j.phymed.2012.09.008. Epub 2012 Oct 23. Phytomedicine. 2012. PMID: 23092722 Free article.
Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog.
Montoia A, Rocha E Silva LF, Torres ZE, Costa DS, Henrique MC, Lima ES, Vasconcellos MC, Souza RC, Costa MR, Grafov A, Grafova I, Eberlin MN, Tadei WP, Amorim RC, Pohlit AM. Montoia A, et al. Among authors: tadei wp. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. Epub 2014 Apr 28. Bioorg Med Chem Lett. 2014. PMID: 24813729
In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives.
Rocha e Silva LF, Nogueira KL, Pinto AC, Katzin AM, Sussmann RA, Muniz MP, de Andrade Neto VF, Chaves FC, Coutinho JP, Lima ES, Krettli AU, Tadei WP, Pohlit AM. Rocha e Silva LF, et al. Among authors: tadei wp. Antimicrob Agents Chemother. 2015;59(6):3271-80. doi: 10.1128/AAC.05012-14. Epub 2015 Mar 23. Antimicrob Agents Chemother. 2015. PMID: 25801563 Free PMC article.
In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon.
Lima RB, Rocha e Silva LF, Melo MR, Costa JS, Picanço NS, Lima ES, Vasconcellos MC, Boleti AP, Santos JM, Amorim RC, Chaves FC, Coutinho JP, Tadei WP, Krettli AU, Pohlit AM. Lima RB, et al. Among authors: tadei wp. Malar J. 2015 Dec 18;14:508. doi: 10.1186/s12936-015-0999-2. Malar J. 2015. PMID: 26682750 Free PMC article.
95 results