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Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression.
Hemming ML, Bhola P, Loycano MA, Anderson JA, Taddei ML, Doyle LA, Lavrova E, Andersen JL, Klega KS, Benson MR, Crompton BD, Raut CP, George S, Letai A, Demetri GD, Sicinska E. Hemming ML, et al. Among authors: taddei ml. Clin Cancer Res. 2022 Jun 1;28(11):2397-2408. doi: 10.1158/1078-0432.CCR-21-3523. Clin Cancer Res. 2022. PMID: 35325095 Free PMC article.
MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor.
Hemming ML, Benson MR, Loycano MA, Anderson JA, Andersen JL, Taddei ML, Krivtsov AV, Aubrey BJ, Cutler JA, Hatton C, Sicinska E, Armstrong SA. Hemming ML, et al. Among authors: taddei ml. Cancer Discov. 2022 Jul 6;12(7):1804-1823. doi: 10.1158/2159-8290.CD-21-0646. Cancer Discov. 2022. PMID: 35499757 Free PMC article.
Metabolic challengers selecting tumor-persistent cells.
Mancini C, Lori G, Pranzini E, Taddei ML. Mancini C, et al. Among authors: taddei ml. Trends Endocrinol Metab. 2024 Mar;35(3):263-276. doi: 10.1016/j.tem.2023.11.005. Epub 2023 Dec 9. Trends Endocrinol Metab. 2024. PMID: 38071164 Review.
Blockade of IL-10 Signaling Ensures Mifamurtide Efficacy in Metastatic Osteosarcoma.
Nastasi N, Pasha A, Bruno G, Subbiani A, Pietrovito L, Leo A, Scala L, de Simone L, Casazza G, Lunardi F, Taddei ML, Tamburini A, Tondo A, Favre C, Calvani M. Nastasi N, et al. Among authors: taddei ml. Cancers (Basel). 2023 Sep 27;15(19):4744. doi: 10.3390/cancers15194744. Cancers (Basel). 2023. PMID: 37835437 Free PMC article.
Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer.
Pardella E, Pranzini E, Nesi I, Parri M, Spatafora P, Torre E, Muccilli A, Castiglione F, Fambrini M, Sorbi F, Cirri P, Caselli A, Puhr M, Klocker H, Serni S, Raugei G, Magherini F, Taddei ML. Pardella E, et al. Among authors: taddei ml. Cells. 2022 Dec 13;11(24):4026. doi: 10.3390/cells11244026. Cells. 2022. PMID: 36552790 Free PMC article.
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis.
Pranzini E, Pardella E, Muccillo L, Leo A, Nesi I, Santi A, Parri M, Zhang T, Uribe AH, Lottini T, Sabatino L, Caselli A, Arcangeli A, Raugei G, Colantuoni V, Cirri P, Chiarugi P, Maddocks ODK, Paoli P, Taddei ML. Pranzini E, et al. Among authors: taddei ml. Cell Rep. 2022 Aug 16;40(7):111233. doi: 10.1016/j.celrep.2022.111233. Cell Rep. 2022. PMID: 35977477 Free article.
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