Tabata Y - Search Results

1

Endocrinological properties of two novel nonsteroidal progesterone receptor modulators, CP8816 and CP8863.

Kurata Y, Tabata Y, Shinei R, Iizuka Y, Masuda NT, Kurihara K, Okonogi T, Hoshiko S. Kurata Y, et al. Among authors: tabata y. J Pharmacol Exp Ther. 2005 May;313(2):916-20. doi: 10.1124/jpet.104.074146. Epub 2005 Mar 2. J Pharmacol Exp Ther. 2005. PMID: 15743919

We have isolated PF1092A, B, and C, novel nonsteroidal progesterone ligands with preferential affinity for the progesterone receptor, from fermentation broth of a fungus [Tabata Y, Miike N, Hatsu M, Kurata Y, Yaguchi T, Someya A, Miyadoh S, Hoshiko S, Tsuruok …

We have isolated PF1092A, B, and C, novel nonsteroidal progesterone ligands with preferential affinity for the progesterone receptor, from f …

2

PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. I. Taxonomy of producing strain, fermentation, isolation and biological activities.

Tabata Y, Miike N, Hatsu M, Kurata Y, Yaguchi T, Someya A, Miyadoh S, Hoshiko S, Tsuruoka T, Omoto S. Tabata Y, et al. J Antibiot (Tokyo). 1997 Apr;50(4):304-8. doi: 10.7164/antibiotics.50.304. J Antibiot (Tokyo). 1997. PMID: 9186554 Free article.

3

PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. II. Physico-chemical properties and structure elucidation.

Tabata Y, Hatsu M, Kurata Y, Miyajima K, Tani M, Sasaki T, Kodama Y, Tsuruoka T, Omoto S. Tabata Y, et al. J Antibiot (Tokyo). 1997 Apr;50(4):309-13. doi: 10.7164/antibiotics.50.309. J Antibiot (Tokyo). 1997. PMID: 9186555 Free article.

4

Diazaphilonic acid, a new azaphilone with telomerase inhibitory activity.

Tabata Y, Ikegami S, Yaguchi T, Sasaki T, Hoshiko S, Sakuma S, Shin-Ya K, Seto H. Tabata Y, et al. J Antibiot (Tokyo). 1999 Apr;52(4):412-4. doi: 10.7164/antibiotics.52.412. J Antibiot (Tokyo). 1999. PMID: 10395277 Free article. No abstract available.

5

Fungal metabolites, PF1092 compounds and their derivatives, are nonsteroidal and selective progesterone receptor modulators.

Tabata Y, Iizuka Y, Kashiwa J, Masuda NT, Shinei R, Kurihara K, Okonogi T, Hoshiko S, Kurata Y. Tabata Y, et al. Eur J Pharmacol. 2001 Nov 2;430(2-3):159-65. doi: 10.1016/s0014-2999(01)01382-6. Eur J Pharmacol. 2001. PMID: 11711027

6

Priming effects of novel nonsteroidal progesterone receptor modulators CP8816 and CP8863 on the development of adenomyosis in the mouse uterus.

Mori T, Kurata Y, Tabata Y, Niho N, Matsuda M, Zhou YF. Mori T, et al. Among authors: tabata y. Life Sci. 2002 Jun 21;71(5):527-35. doi: 10.1016/s0024-3205(02)01727-7. Life Sci. 2002. PMID: 12052437

7

In vitro and in vivo characterization of novel nonsteroidal progesterone receptor antagonists derived from the fungal metabolite PF1092C.

Tabata Y, Iizuka Y, Masuda NT, Shinei R, Kurihara Ki, Okonogi T, Hoshiko S, Kurata Y. Tabata Y, et al. J Steroid Biochem Mol Biol. 2002 Oct;82(2-3):217-23. doi: 10.1016/s0960-0760(02)00157-7. J Steroid Biochem Mol Biol. 2002. PMID: 12477488

8

CP8668, a novel orally active nonsteroidal progesterone receptor modulator with tetrahydrobenzindolone skeleton.

Tabata Y, Iizuka Y, Shinei R, Kurihara K, Okonogi T, Hoshiko S, Kurata Y. Tabata Y, et al. Eur J Pharmacol. 2003 Feb 7;461(1):73-8. doi: 10.1016/s0014-2999(02)02958-8. Eur J Pharmacol. 2003. PMID: 12568918

9

Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor.

Kakui N, Tanaka J, Tabata Y, Asai K, Masuda N, Miyara T, Nakatani Y, Ohsawa F, Nishikawa N, Sugai M, Suzuki M, Aoki K, Kitaguchi H. Kakui N, et al. Among authors: tabata y. J Pharmacol Exp Ther. 2006 May;317(2):562-70. doi: 10.1124/jpet.105.099705. Epub 2006 Jan 25. J Pharmacol Exp Ther. 2006. PMID: 16436501

10

Nonsteroidal progesterone receptor ligands (II); synthesis and SAR of new tetrahydrobenzindolone derivatives.

Kurihara K, Shinei R, Tanabe K, Tabata Y, Kurata Y, Hoshiko S, Okonogi T. Kurihara K, et al. Among authors: tabata y. Bioorg Med Chem. 2006 Jul 15;14(14):4862-78. doi: 10.1016/j.bmc.2006.03.022. Epub 2006 Mar 31. Bioorg Med Chem. 2006. PMID: 16580209

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