Taatjes DJ - Search Results

1

Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma.

Maia-Silva D, Schier AC, Skopelitis D, Kechejian V, Alpsoy A, Liverpool J, Taatjes DJ, Vakoc CR. Maia-Silva D, et al. Among authors: taatjes dj. bioRxiv [Preprint]. 2023 Oct 27:2023.10.24.563848. doi: 10.1101/2023.10.24.563848. bioRxiv. 2023. PMID: 37961243 Free PMC article. Preprint.

2

Structure and mechanism of the RNA polymerase II transcription machinery.

Schier AC, Taatjes DJ. Schier AC, et al. Among authors: taatjes dj. Genes Dev. 2020 Apr 1;34(7-8):465-488. doi: 10.1101/gad.335679.119. Genes Dev. 2020. PMID: 32238450 Free PMC article. Review.

3

Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription.

Schier AC, Taatjes DJ. Schier AC, et al. Among authors: taatjes dj. Nat Struct Mol Biol. 2021 Jul;28(7):540-543. doi: 10.1038/s41594-021-00613-6. Nat Struct Mol Biol. 2021. PMID: 34131334 Free PMC article.

4

Regulatory functions of the Mediator kinases CDK8 and CDK19.

Fant CB, Taatjes DJ. Fant CB, et al. Among authors: taatjes dj. Transcription. 2019 Apr;10(2):76-90. doi: 10.1080/21541264.2018.1556915. Epub 2018 Dec 26. Transcription. 2019. PMID: 30585107 Free PMC article. Review.

5

RNA Polymerase II Transcription.

Taatjes DJ. Taatjes DJ. J Mol Biol. 2021 Jul 9;433(14):167037. doi: 10.1016/j.jmb.2021.167037. Epub 2021 May 4. J Mol Biol. 2021. PMID: 33957145 Free PMC article. No abstract available.

6

Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription.

Palacio M, Taatjes DJ. Palacio M, et al. Among authors: taatjes dj. J Mol Biol. 2022 Jan 15;434(1):167216. doi: 10.1016/j.jmb.2021.167216. Epub 2021 Aug 30. J Mol Biol. 2022. PMID: 34474085 Free PMC article. Review.

7

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome.

Cozzolino K, Sanford L, Hunter S, Molison K, Erickson B, Jones T, Ajit D, Galbraith MD, Espinosa JM, Bentley DL, Allen MA, Dowell RD, Taatjes DJ. Cozzolino K, et al. Among authors: taatjes dj. bioRxiv [Preprint]. 2023 Dec 13:2023.07.05.547813. doi: 10.1101/2023.07.05.547813. bioRxiv. 2023. PMID: 37461585 Free PMC article. Preprint.

8

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator.

Knuesel MT, Meyer KD, Donner AJ, Espinosa JM, Taatjes DJ. Knuesel MT, et al. Among authors: taatjes dj. Mol Cell Biol. 2009 Feb;29(3):650-61. doi: 10.1128/MCB.00993-08. Epub 2008 Dec 1. Mol Cell Biol. 2009. PMID: 19047373 Free PMC article.

9

p53 activates transcription by directing structural shifts in Mediator.

Meyer KD, Lin SC, Bernecky C, Gao Y, Taatjes DJ. Meyer KD, et al. Among authors: taatjes dj. Nat Struct Mol Biol. 2010 Jun;17(6):753-60. doi: 10.1038/nsmb.1816. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453859 Free PMC article.

10

Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly.

Bernecky C, Taatjes DJ. Bernecky C, et al. Among authors: taatjes dj. J Mol Biol. 2012 Apr 13;417(5):387-94. doi: 10.1016/j.jmb.2012.02.014. Epub 2012 Feb 16. J Mol Biol. 2012. PMID: 22343046 Free PMC article.

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