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Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome.
Cozzolino K, Sanford L, Hunter S, Molison K, Erickson B, Jones T, Ajit D, Galbraith MD, Espinosa JM, Bentley DL, Allen MA, Dowell RD, Taatjes DJ. Cozzolino K, et al. Among authors: taatjes dj. bioRxiv [Preprint]. 2023 Dec 13:2023.07.05.547813. doi: 10.1101/2023.07.05.547813. bioRxiv. 2023. PMID: 37461585 Free PMC article. Preprint.
A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.
Audetat KA, Galbraith MD, Odell AT, Lee T, Pandey A, Espinosa JM, Dowell RD, Taatjes DJ. Audetat KA, et al. Among authors: taatjes dj. Mol Cell Biol. 2017 Jun 15;37(13):e00626-16. doi: 10.1128/MCB.00626-16. Print 2017 Jul 1. Mol Cell Biol. 2017. PMID: 28416637 Free PMC article.
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.
Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Ebmeier CC, et al. Among authors: taatjes dj. Cell Rep. 2017 Aug 1;20(5):1173-1186. doi: 10.1016/j.celrep.2017.07.021. Cell Rep. 2017. PMID: 28768201 Free PMC article.
Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, Dowell RD, Taatjes DJ, Kovarik P. Steinparzer I, et al. Among authors: taatjes dj. Mol Cell. 2019 Nov 7;76(3):485-499.e8. doi: 10.1016/j.molcel.2019.07.034. Epub 2019 Sep 5. Mol Cell. 2019. PMID: 31495563 Free PMC article.
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription.
Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, Tao L, DeRoy P, Clavette C, Nayak S, Damon LJ, Kaltheuner IH, Bunch H, Cantley LC, Geyer M, Iwasa J, Dowell RD, Bentley DL, Old WM, Taatjes DJ. Rimel JK, et al. Among authors: taatjes dj. Genes Dev. 2020 Nov 1;34(21-22):1452-1473. doi: 10.1101/gad.341545.120. Epub 2020 Oct 15. Genes Dev. 2020. PMID: 33060135 Free PMC article.
352 results