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Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein.
Lanning ME, Yu W, Yap JL, Chauhan J, Chen L, Whiting E, Pidugu LS, Atkinson T, Bailey H, Li W, Roth BM, Hynicka L, Chesko K, Toth EA, Shapiro P, MacKerell AD Jr, Wilder PT, Fletcher S. Lanning ME, et al. Eur J Med Chem. 2016 May 4;113:273-92. doi: 10.1016/j.ejmech.2016.02.006. Epub 2016 Feb 4. Eur J Med Chem. 2016. PMID: 26985630 Free PMC article.
Thiophene-expanded guanosine analogues of Gemcitabine.
Chen Z, Ku TC, Seley-Radtke KL. Chen Z, et al. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4274-6. doi: 10.1016/j.bmcl.2015.07.086. Epub 2015 Jul 30. Bioorg Med Chem Lett. 2015. PMID: 26316465 Free PMC article.
Type IV pilus secretins have extracellular C termini.
Lieberman JA, Petro CD, Thomas S, Yang A, Donnenberg MS. Lieberman JA, et al. mBio. 2015 Mar 24;6(2):e00322-15. doi: 10.1128/mBio.00322-15. mBio. 2015. PMID: 25805731 Free PMC article.
12 results