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N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.
J Med Chem. 2011 Oct 13;54(19):6843-58. doi: 10.1021/jm200794r. Epub 2011 Sep 15.
J Med Chem. 2011.
PMID: 21859126
Free PMC article.
Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin "Trojan Horse" antibiotics and synthetic desferridanoxamine-antibiotic conjugates.
Wencewicz TA, Möllmann U, Long TE, Miller MJ.
Wencewicz TA, et al.
Biometals. 2009 Aug;22(4):633-48. doi: 10.1007/s10534-009-9218-3. Epub 2009 Feb 17.
Biometals. 2009.
PMID: 19221879
Free PMC article.
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