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IL-15 and N-803 for HIV Cure Approaches.
Howard JN, Bosque A. Howard JN, et al. Viruses. 2023 Sep 12;15(9):1912. doi: 10.3390/v15091912. Viruses. 2023. PMID: 37766318 Free PMC article. Review.
The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.
Copertino DC Jr, Holmberg CS, Weiler J, Ward AR, Howard JN, Levinger C, Pang AP, Corley MJ, Dündar F, Zumbo P, Betel D, Gandhi RT, McMahon DK, Bosch RJ, Linden N, Macatangay BJ, Cyktor JC, Eron JJ, Mellors JW, Kovacs C, Benko E, Bosque A, Jones RB; AIDS Clinical Trials Group (ACTG) A5321 Team. Copertino DC Jr, et al. JCI Insight. 2023 Sep 22;8(18):e169028. doi: 10.1172/jci.insight.169028. JCI Insight. 2023. PMID: 37581929 Free PMC article.
Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent HIV.
Ghofrani J, Bowen A, Chen J, Balakrishnan PB, Powell AB, Cherukula K, Cruz CRY, Jones RB, Lynch RM, Sweeney EE, Fernandes R. Ghofrani J, et al. Int J Nanomedicine. 2023 Jul 25;18:4055-4066. doi: 10.2147/IJN.S401304. eCollection 2023. Int J Nanomedicine. 2023. PMID: 37520301 Free PMC article.