T32 AI148103/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: T32 AI148103/AI/NIAID NIH HHS/United States[Grant - PubMed

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Results by year

Year	Number of Results
2020	4
2021	5
2022	5
2023	6
2024	2

19 results

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Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors.

Ghosh AK, Yadav M, Iddum S, Ghazi S, Lendy EK, Jayashankar U, Beechboard SN, Takamatsu Y, Hattori SI, Aamano M, Higashi-Kuwata N, Mitsuya H, Mesecar AD. Ghosh AK, et al. Eur J Med Chem. 2024 Mar 5;267:116132. doi: 10.1016/j.ejmech.2024.116132. Epub 2024 Feb 1. Eur J Med Chem. 2024. PMID: 38335815

Crystal structure of bacterial ubiquitin ADP-ribosyltransferase CteC reveals a substrate-recruiting insertion.

Zhang Z, Rondon-Cordero HM, Das C. Zhang Z, et al. J Biol Chem. 2024 Feb;300(2):105604. doi: 10.1016/j.jbc.2023.105604. Epub 2023 Dec 28. J Biol Chem. 2024. PMID: 38159861 Free PMC article.

An expanded toolkit of drug resistance cassettes for Candida glabrata, Candida auris, and Candida albicans leads to new insights into the ergosterol pathway.

Gregor JB, Gutierrez-Schultz VA, Hoda S, Baker KM, Saha D, Burghaze MG, Vazquez C, Burgei KE, Briggs SD. Gregor JB, et al. mSphere. 2023 Dec 20;8(6):e0031123. doi: 10.1128/msphere.00311-23. Epub 2023 Nov 6. mSphere. 2023. PMID: 37929964 Free PMC article.

Rapid, efficient auxin-inducible protein degradation in Candida pathogens.

Milholland KL, Gregor JB, Hoda S, Píriz-Antúnez S, Dueñas-Santero E, Vu BG, Patel KP, Moye-Rowley WS, Vázquez de Aldana CR, Correa-Bordes J, Briggs SD, Hall MC. Milholland KL, et al. mSphere. 2023 Oct 24;8(5):e0028323. doi: 10.1128/msphere.00283-23. Epub 2023 Aug 18. mSphere. 2023. PMID: 37594261 Free PMC article.

Engineered Vancomycin, with Increased Interactions with Peptidoglycan Stem Peptide, Conquers Non-tuberculosis Mycobacteria.

Vennard C, Oropo T, Sintim HO. Vennard C, et al. J Med Chem. 2023 Aug 10;66(15):10238-10240. doi: 10.1021/acs.jmedchem.3c01219. Epub 2023 Jul 21. J Med Chem. 2023. PMID: 37477251

Expanding the toolkit for genetic manipulation and discovery in Candida species using a CRISPR ribonucleoprotein-based approach.

Gregor JB, Gutierrez-Schultz VA, Hoda S, Baker KM, Saha D, Burghaze MG, Briggs SD. Gregor JB, et al. bioRxiv [Preprint]. 2023 Jun 17:2023.06.16.545382. doi: 10.1101/2023.06.16.545382. bioRxiv. 2023. PMID: 37398038 Free PMC article. Preprint.

Rapid, efficient auxin-inducible protein degradation in Candida pathogens.

Milholland KL, Gregor JB, Hoda S, Píriz-Antúnez S, Dueñas-Santero E, Vu BG, Patel KP, Moye-Rowley WS, de Aldana CRV, Correa-Bordes J, Briggs SD, Hall MC. Milholland KL, et al. bioRxiv [Preprint]. 2023 May 18:2023.05.17.541235. doi: 10.1101/2023.05.17.541235. bioRxiv. 2023. PMID: 37293017 Free PMC article. Updated. Preprint.

An Expanding Role of 2',3'-Cyclic Nucleotide Monophosphates in Bacteria.

Vennard C, Sintim HO. Vennard C, et al. ACS Cent Sci. 2022 Nov 23;8(11):1480-1483. doi: 10.1021/acscentsci.2c01184. Epub 2022 Nov 15. ACS Cent Sci. 2022. PMID: 36439309 Free PMC article. No abstract available.

Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding.

Husby ML, Amiar S, Prugar LI, David EA, Plescia CB, Huie KE, Brannan JM, Dye JM, Pienaar E, Stahelin RV. Husby ML, et al. EMBO Rep. 2022 Nov 7;23(11):e51709. doi: 10.15252/embr.202051709. Epub 2022 Sep 12. EMBO Rep. 2022. PMID: 36094794 Free PMC article.

Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic.

Naclerio GA, Abutaleb NS, Onyedibe KI, Karanja C, Eldesouky HE, Liang HW, Dieterly A, Aryal UK, Lyle T, Seleem MN, Sintim HO. Naclerio GA, et al. J Med Chem. 2022 May 12;65(9):6612-6630. doi: 10.1021/acs.jmedchem.1c02034. Epub 2022 Apr 28. J Med Chem. 2022. PMID: 35482444 Free PMC article.

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