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HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation.
Nat Immunol. 2009 May;10(5):540-50. doi: 10.1038/ni.1725. Epub 2009 Apr 12.
Nat Immunol. 2009.
PMID: 19363484
Free PMC article.
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination.
Xu Z, Pone EJ, Al-Qahtani A, Park SR, Zan H, Casali P.
Xu Z, et al.
Crit Rev Immunol. 2007;27(4):367-97. doi: 10.1615/critrevimmunol.v27.i4.60.
Crit Rev Immunol. 2007.
PMID: 18197815
Free PMC article.
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