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Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.
Piekielna-Ciesielska J, Mollica A, Pieretti S, Fichna J, Szymaszkiewicz A, Zielińska M, Kordek R, Janecka A. Piekielna-Ciesielska J, et al. Among authors: szymaszkiewicz a. J Enzyme Inhib Med Chem. 2018 Dec;33(1):560-566. doi: 10.1080/14756366.2018.1441839. J Enzyme Inhib Med Chem. 2018. PMID: 29513114 Free PMC article.
Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and KOP opioid receptors, exerts anti-inflammatory and anti-tumor activity in colitis and colitis-associated colorectal cancer in mice.
Zielińska M, Szymaszkiewicz A, Jacenik D, Schodel L, Sałaga M, Zatorski H, Kordek R, Becker C, Krajewska WM, Fichna J. Zielińska M, et al. Among authors: szymaszkiewicz a. Eur J Pharmacol. 2020 Oct 15;885:173463. doi: 10.1016/j.ejphar.2020.173463. Epub 2020 Aug 22. Eur J Pharmacol. 2020. PMID: 32835668
Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders.
DiCello JJ, Carbone SE, Saito A, Pham V, Szymaszkiewicz A, Gondin AB, Alvi S, Marique K, Shenoy P, Veldhuis NA, Fichna J, Canals M, Christopoulos A, Valant C, Poole DP. DiCello JJ, et al. Among authors: szymaszkiewicz a. Am J Physiol Gastrointest Liver Physiol. 2022 Jan 1;322(1):G66-G78. doi: 10.1152/ajpgi.00297.2021. Epub 2021 Nov 10. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 34755545 Free article.
19 results