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Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Ross JL, Chen Z, Herting CJ, Grabovska Y, Szulzewsky F, Puigdelloses M, Monterroza L, Switchenko J, Wadhwani NR, Cimino PJ, Mackay A, Jones C, Read RD, MacDonald TJ, Schniederjan M, Becher OJ, Hambardzumyan D. Ross JL, et al. Among authors: szulzewsky f. Brain. 2021 Feb 12;144(1):53-69. doi: 10.1093/brain/awaa382. Brain. 2021. PMID: 33300045 Free PMC article.
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis.
Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen RD, Alvarez-Garcia V, Kim Y, Wang B, Tamagno I, Zhou H, Li X, Kettenmann H, Ransohoff RM, Hambardzumyan D. Feng X, et al. Among authors: szulzewsky f. Oncotarget. 2015 Jun 20;6(17):15077-94. doi: 10.18632/oncotarget.3730. Oncotarget. 2015. PMID: 25987130 Free PMC article.
Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma.
Cimino PJ, Kim Y, Wu HJ, Alexander J, Wirsching HG, Szulzewsky F, Pitter K, Ozawa T, Wang J, Vazquez J, Arora S, Rabadan R, Levine R, Michor F, Holland EC. Cimino PJ, et al. Among authors: szulzewsky f. Genes Dev. 2018 Apr 1;32(7-8):512-523. doi: 10.1101/gad.312157.118. Epub 2018 Apr 9. Genes Dev. 2018. PMID: 29632085 Free PMC article.
Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma.
Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC. Wirsching HG, et al. Among authors: szulzewsky f. JCI Insight. 2019 Jul 11;4(13):e128217. doi: 10.1172/jci.insight.128217. eCollection 2019 Jul 11. JCI Insight. 2019. PMID: 31292299 Free PMC article.
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Kettenmann H, Brennan CW, Brat DJ, Hambardzumyan D. Kaffes I, et al. Among authors: szulzewsky f. Oncoimmunology. 2019 Aug 22;8(11):e1655360. doi: 10.1080/2162402X.2019.1655360. eCollection 2019. Oncoimmunology. 2019. PMID: 31646100 Free PMC article.
46 results