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Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice.
Sun B, Rouzbehani OMT, Kramer RJ, Ghosh R, Perelli RM, Atkins S, Fatahian AN, Davis K, Szulik MW, Goodman MA, Hathaway MA, Chi E, Word TA, Tunuguntla H, Denfield SW, Wehrens XHT, Whitehead KJ, Abdelnasser HY, Warren JS, Wu M, Franklin S, Boudina S, Landstrom AP. Sun B, et al. Among authors: szulik mw. Circ Heart Fail. 2023 Dec;16(12):e010351. doi: 10.1161/CIRCHEARTFAILURE.122.010351. Epub 2023 Dec 19. Circ Heart Fail. 2023. PMID: 38113297
SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation.
Szulik MW, Valdez S, Walsh M, Davis K, Bia R, Horiuchi E, O'Very S, Laxman AK, Sandaklie-Nicolova L, Eberhardt DR, Durrant JR, Sheikh H, Hickenlooper S, Creed M, Brady C, Miller M, Wang L, Garcia-Llana J, Tracy C, Drakos SG, Funai K, Chaudhuri D, Boudina S, Franklin S. Szulik MW, et al. Basic Res Cardiol. 2023 May 22;118(1):20. doi: 10.1007/s00395-023-00991-6. Basic Res Cardiol. 2023. PMID: 37212935 Free PMC article.
Histone H4K20 Trimethylation Is Decreased in Murine Models of Heart Disease.
Hickenlooper SM, Davis K, Szulik MW, Sheikh H, Miller M, Valdez S, Bia R, Franklin S. Hickenlooper SM, et al. Among authors: szulik mw. ACS Omega. 2022 Aug 23;7(35):30710-30719. doi: 10.1021/acsomega.2c00984. eCollection 2022 Sep 6. ACS Omega. 2022. PMID: 36092581 Free PMC article.
Author Correction: Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D. Balderas E, et al. Among authors: szulik mw. Nat Commun. 2022 Jun 20;13(1):3532. doi: 10.1038/s41467-022-31304-5. Nat Commun. 2022. PMID: 35725853 Free PMC article. No abstract available.
Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D. Balderas E, et al. Among authors: szulik mw. Nat Commun. 2022 May 19;13(1):2769. doi: 10.1038/s41467-022-30236-4. Nat Commun. 2022. PMID: 35589699 Free PMC article.
The role of demethylases in cardiac development and disease.
Davis K, Azarcon P, Hickenlooper S, Bia R, Horiuchi E, Szulik MW, Franklin S. Davis K, et al. Among authors: szulik mw. J Mol Cell Cardiol. 2021 Sep;158:89-100. doi: 10.1016/j.yjmcc.2021.05.018. Epub 2021 May 31. J Mol Cell Cardiol. 2021. PMID: 34081951 Review.
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.
Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S. Warren JS, et al. Among authors: szulik mw. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7871-E7880. doi: 10.1073/pnas.1800680115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061404 Free PMC article.
16 results