Szombathelyi Z - Search Results

1

Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones.

Nagy J, Kolok S, Dezso P, Boros A, Szombathelyi Z. Nagy J, et al. Among authors: szombathelyi z. Neurochem Int. 2003 Jan;42(1):35-43. doi: 10.1016/s0197-0186(02)00062-1. Neurochem Int. 2003. PMID: 12441166

2

NR2B subunit selective NMDA antagonists inhibit neurotoxic effect of alcohol-withdrawal in primary cultures of rat cortical neurones.

Nagy J, Horváth C, Farkas S, Kolok S, Szombathelyi Z. Nagy J, et al. Among authors: szombathelyi z. Neurochem Int. 2004 Jan;44(1):17-23. doi: 10.1016/s0197-0186(03)00100-1. Neurochem Int. 2004. PMID: 12963084

3

Inducible expression and pharmacological characterization of recombinant rat NR1a/NR2A NMDA receptors.

Kurkó D, Dezso P, Boros A, Kolok S, Fodor L, Nagy J, Szombathelyi Z. Kurkó D, et al. Among authors: szombathelyi z. Neurochem Int. 2005 Apr;46(5):369-79. doi: 10.1016/j.neuint.2004.12.002. Neurochem Int. 2005. PMID: 15737435

4

Flow cytometry-based method to analyze the change in Tau phosphorylation in a hGSK-3beta and hTau over-expressing EcR-293 cell line.

Kurko D, Boros A, Dezso P, Urbányi Z, Sárvári M, Nagy J, Szombathelyi Z, Szendrei GI. Kurko D, et al. Among authors: szombathelyi z. Neurochem Int. 2006 Apr;48(5):374-82. doi: 10.1016/j.neuint.2005.11.010. Epub 2006 Jan 18. Neurochem Int. 2006. PMID: 16420965

5

Functional characterization of sodium channel blockers by membrane potential measurements in cerebellar neurons: prediction of compound preference for the open/inactivated state.

Kolok S, Nagy J, Szombathelyi Z, Tarnawa I. Kolok S, et al. Among authors: szombathelyi z. Neurochem Int. 2006 Nov;49(6):593-604. doi: 10.1016/j.neuint.2006.04.014. Epub 2006 Jun 13. Neurochem Int. 2006. PMID: 16777267

6

Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins.

Kurko D, Bekes Z, Gere A, Baki A, Boros A, Kolok S, Bugovics G, Nagy J, Szombathelyi Z, Ignácz-Szendrei G. Kurko D, et al. Among authors: szombathelyi z. Neurochem Int. 2009 Dec;55(7):467-75. doi: 10.1016/j.neuint.2009.04.015. Epub 2009 May 6. Neurochem Int. 2009. PMID: 19426776

7

Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs.

Wágner G, Wéber C, Nyéki O, Nógrádi K, Bielik A, Molnár L, Bobok A, Horváth A, Kiss B, Kolok S, Nagy J, Kurkó D, Gál K, Greiner I, Szombathelyi Z, Keseru GM, Domány G. Wágner G, et al. Among authors: szombathelyi z. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3737-41. doi: 10.1016/j.bmcl.2010.04.075. Epub 2010 Apr 22. Bioorg Med Chem Lett. 2010. PMID: 20483612

8

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists.

Galambos J, Wágner G, Nógrádi K, Bielik A, Molnár L, Bobok A, Horváth A, Kiss B, Kolok S, Nagy J, Kurkó D, Bakk ML, Vastag M, Sághy K, Gyertyán I, Gál K, Greiner I, Szombathelyi Z, Keseru GM, Domány G. Galambos J, et al. Among authors: szombathelyi z. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4371-5. doi: 10.1016/j.bmcl.2010.06.075. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615697

9

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: Lead optimization.

Nógrádi K, Wágner G, Domány G, Bobok A, Magdó I, Kolok S, Mikó-Bakk ML, Vastag M, Sághy K, Gyertyán I, Kóti J, Gál K, Farkas S, Keserű GM, Greiner I, Szombathelyi Z. Nógrádi K, et al. Among authors: szombathelyi z. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1724-1729. doi: 10.1016/j.bmcl.2015.02.073. Epub 2015 Mar 7. Bioorg Med Chem Lett. 2015. PMID: 25791451

10

4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate.

Galambos J, Domány G, Nógrádi K, Wágner G, Keserű GM, Bobok A, Kolok S, Mikó-Bakk ML, Vastag M, Sághy K, Kóti J, Szakács Z, Béni Z, Gál K, Szombathelyi Z, Greiner I. Galambos J, et al. Among authors: szombathelyi z. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1249-52. doi: 10.1016/j.bmcl.2016.01.024. Epub 2016 Jan 11. Bioorg Med Chem Lett. 2016. PMID: 26774652

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