Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Rational design of balanced dual-targeting antibiotics with limited resistance.
Nyerges A, Tomašič T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, Foldesi I, Kata D, Welin M, Kimbung R, Focht D, Mašič LP, Pal C. Nyerges A, et al. Among authors: szili p. PLoS Biol. 2020 Oct 5;18(10):e3000819. doi: 10.1371/journal.pbio.3000819. eCollection 2020 Oct. PLoS Biol. 2020. PMID: 33017402 Free PMC article.
Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.
Nyerges Á, Csörgő B, Draskovits G, Kintses B, Szili P, Ferenc G, Révész T, Ari E, Nagy I, Bálint B, Vásárhelyi BM, Bihari P, Számel M, Balogh D, Papp H, Kalapis D, Papp B, Pál C. Nyerges Á, et al. Among authors: szili p. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5726-E5735. doi: 10.1073/pnas.1801646115. Epub 2018 Jun 5. Proc Natl Acad Sci U S A. 2018. PMID: 29871954 Free PMC article.
Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations.
Szili P, Draskovits G, Révész T, Bogár F, Balogh D, Martinek T, Daruka L, Spohn R, Vásárhelyi BM, Czikkely M, Kintses B, Grézal G, Ferenc G, Pál C, Nyerges Á. Szili P, et al. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00207-19. doi: 10.1128/AAC.00207-19. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31235632 Free PMC article.
Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity.
Fois B, Skok Ž, Tomašič T, Ilaš J, Zidar N, Zega A, Peterlin Mašič L, Szili P, Draskovits G, Nyerges Á, Pál C, Kikelj D. Fois B, et al. Among authors: szili p. ChemMedChem. 2020 Feb 5;15(3):265-269. doi: 10.1002/cmdc.201900607. Epub 2019 Dec 10. ChemMedChem. 2020. PMID: 31721445
Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors.
Lamut A, Skok Ž, Barančoková M, Gutierrez LJ, Cruz CD, Tammela P, Draskovits G, Szili PÉ, Nyerges Á, Pál C, Molek P, Bratkovič T, Ilaš J, Zidar N, Zega A, Enriz RD, Kikelj D, Tomašič T. Lamut A, et al. Among authors: szili pe. Future Med Chem. 2020 Feb;12(4):277-297. doi: 10.4155/fmc-2019-0127. Epub 2020 Feb 11. Future Med Chem. 2020. PMID: 32043377
Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation.
Durcik M, Skok Ž, Ilaš J, Zidar N, Zega A, Szili PÉ, Draskovits G, Révész T, Kikelj D, Nyerges A, Pál C, Mašič LP, Tomašič T. Durcik M, et al. Among authors: szili pe. Pharmaceutics. 2020 Dec 22;13(1):6. doi: 10.3390/pharmaceutics13010006. Pharmaceutics. 2020. PMID: 33374964 Free PMC article.
New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.
Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašič LP, Tomašič T. Durcik M, et al. Among authors: szili pe. Eur J Med Chem. 2021 Mar 5;213:113200. doi: 10.1016/j.ejmech.2021.113200. Epub 2021 Jan 22. Eur J Med Chem. 2021. PMID: 33524686
Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.
Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B. Apjok G, et al. Among authors: szili p. Nat Microbiol. 2023 Mar;8(3):410-423. doi: 10.1038/s41564-023-01320-2. Epub 2023 Feb 9. Nat Microbiol. 2023. PMID: 36759752 Free PMC article.
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus.
Durcik M, Cotman AE, Toplak Ž, Možina Š, Skok Ž, Szili PE, Czikkely M, Maharramov E, Vu TH, Piras MV, Zidar N, Ilaš J, Zega A, Trontelj J, Pardo LA, Hughes D, Huseby D, Berruga-Fernández T, Cao S, Simoff I, Svensson R, Korol SV, Jin Z, Vicente F, Ramos MC, Mundy JEA, Maxwell A, Stevenson CEM, Lawson DM, Glinghammar B, Sjöström E, Bohlin M, Oreskär J, Alvér S, Janssen GV, Sterk GJ, Kikelj D, Pal C, Tomašič T, Peterlin Mašič L. Durcik M, et al. Among authors: szili pe. J Med Chem. 2023 Mar 23;66(6):3968-3994. doi: 10.1021/acs.jmedchem.2c01905. Epub 2023 Mar 6. J Med Chem. 2023. PMID: 36877255 Free PMC article.
12 results