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High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1.
Int J Mol Sci. 2018 May 10;19(5):1435. doi: 10.3390/ijms19051435.
Int J Mol Sci. 2018.
PMID: 29748524
Free PMC article.
The autoinhibitory function of D1 domain of FGFR1 goes beyond the inhibition of ligand binding.
Opalinski L, Szczepara M, Sokolowska-Wedzina A, Zakrzewska M, Otlewski J.
Opalinski L, et al. Among authors: szczepara m.
Int J Biochem Cell Biol. 2017 Aug;89:193-198. doi: 10.1016/j.biocel.2017.06.015. Epub 2017 Jun 23.
Int J Biochem Cell Biol. 2017.
PMID: 28652212
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Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity.
Opaliński Ł, Sokołowska-Wędzina A, Szczepara M, Zakrzewska M, Otlewski J.
Opaliński Ł, et al. Among authors: szczepara m.
Sci Rep. 2017 Aug 2;7(1):7121. doi: 10.1038/s41598-017-07479-z.
Sci Rep. 2017.
PMID: 28769084
Free PMC article.
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