Szakács G - Search Results

1

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.

Ebner J, Schmoellerl J, Piontek M, Manhart G, Troester S, Carter BZ, Neubauer H, Moriggl R, Szakács G, Zuber J, Köcher T, Andreeff M, Sperr WR, Valent P, Grebien F. Ebner J, et al. Among authors: szakacs g. Nat Commun. 2023 Sep 19;14(1):5709. doi: 10.1038/s41467-023-41229-2. Nat Commun. 2023. PMID: 37726279 Free PMC article.

2

Targeting multidrug resistance in cancer.

Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Szakács G, et al. Nat Rev Drug Discov. 2006 Mar;5(3):219-34. doi: 10.1038/nrd1984. Nat Rev Drug Discov. 2006. PMID: 16518375 Review.

3

A mass spectrometry based functional assay for the quantitative assessment of ABC transporter activity.

Katona M, Kiss K, Angyal V, Kucsma N, Sarkadi B, Takáts Z, Szakács G. Katona M, et al. Among authors: szakacs g. Rapid Commun Mass Spectrom. 2009 Nov;23(21):3372-6. doi: 10.1002/rcm.4259. Rapid Commun Mass Spectrom. 2009. PMID: 19780062

4

Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia.

Karászi E, Jakab K, Homolya L, Szakács G, Holló Z, Telek B, Kiss A, Rejtô L, Nahajevszky S, Sarkadi B, Kappelmayer J. Karászi E, et al. Among authors: szakacs g. Br J Haematol. 2001 Feb;112(2):308-14. doi: 10.1046/j.1365-2141.2001.02554.x. Br J Haematol. 2001. PMID: 11167823 Free article.

5

Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.

Ozvegy C, Litman T, Szakács G, Nagy Z, Bates S, Váradi A, Sarkadi B. Ozvegy C, et al. Among authors: szakacs g. Biochem Biophys Res Commun. 2001 Jul 6;285(1):111-7. doi: 10.1006/bbrc.2001.5130. Biochem Biophys Res Commun. 2001. PMID: 11437380

6

Defeating drug resistance in cancer.

Gottesman MM, Ludwig J, Xia D, Szakács G. Gottesman MM, et al. Among authors: szakacs g. Discov Med. 2006 Feb;6(31):18-23. Discov Med. 2006. PMID: 17234123 Free article.

7

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

Szakács G, Váradi A, Ozvegy-Laczka C, Sarkadi B. Szakács G, et al. Drug Discov Today. 2008 May;13(9-10):379-93. doi: 10.1016/j.drudis.2007.12.010. Epub 2008 Feb 20. Drug Discov Today. 2008. PMID: 18468555 Review.

8

Relevance of multidrug resistance in the age of targeted therapy.

Türk D, Szakács G. Türk D, et al. Among authors: szakacs g. Curr Opin Drug Discov Devel. 2009 Mar;12(2):246-52. Curr Opin Drug Discov Devel. 2009. PMID: 19333870 Review.

9

Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?

Brózik A, Hegedüs C, Erdei Z, Hegedus T, Özvegy-Laczka C, Szakács G, Sarkadi B. Brózik A, et al. Among authors: szakacs g. Expert Opin Drug Metab Toxicol. 2011 May;7(5):623-42. doi: 10.1517/17425255.2011.562892. Epub 2011 Mar 17. Expert Opin Drug Metab Toxicol. 2011. PMID: 21410427 Review.

10

The controversial role of ABC transporters in clinical oncology.

Tamaki A, Ierano C, Szakacs G, Robey RW, Bates SE. Tamaki A, et al. Among authors: szakacs g. Essays Biochem. 2011 Sep 7;50(1):209-32. doi: 10.1042/bse0500209. Essays Biochem. 2011. PMID: 21967059 Free PMC article. Review.

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