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New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis.
Castillo AF, Orlando UD, Maloberti PM, Prada JG, Dattilo MA, Solano AR, Bigi MM, Ríos Medrano MA, Torres MT, Indo S, Caroca G, Contreras HR, Marelli BE, Salinas FJ, Salvetti NR, Ortega HH, Lorenzano Menna P, Szajnman S, Gomez DE, Rodríguez JB, Podesta EJ. Castillo AF, et al. Among authors: szajnman s. Cell Mol Life Sci. 2021 Mar;78(6):2893-2910. doi: 10.1007/s00018-020-03679-5. Epub 2020 Oct 17. Cell Mol Life Sci. 2021. PMID: 33068124 Free PMC article.
Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.
Szajnman SH, García Liñares GE, Li ZH, Jiang C, Galizzi M, Bontempi EJ, Ferella M, Moreno SN, Docampo R, Rodriguez JB. Szajnman SH, et al. Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. doi: 10.1016/j.bmc.2007.12.010. Epub 2007 Dec 10. Bioorg Med Chem. 2008. PMID: 18096393 Free PMC article.
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