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Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands.
Szczepańska K, Karcz T, Siwek A, Kuder KJ, Latacz G, Bednarski M, Szafarz M, Hagenow S, Lubelska A, Olejarz-Maciej A, Sobolewski M, Mika K, Kotańska M, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: szafarz m. Bioorg Chem. 2019 Oct;91:103071. doi: 10.1016/j.bioorg.2019.103071. Epub 2019 Jun 20. Bioorg Chem. 2019. PMID: 31362197
KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice.
Kotańska M, Mika K, Reguła K, Szczepańska K, Szafarz M, Bednarski M, Olejarz-Maciej A, Nowak K, Latacz G, Mogilski S, Kuder KJ, Kieć-Kononowicz K, Sapa J. Kotańska M, et al. Among authors: szafarz m. Biochem Pharmacol. 2019 Oct;168:193-203. doi: 10.1016/j.bcp.2019.07.006. Epub 2019 Jul 8. Biochem Pharmacol. 2019. PMID: 31295465
KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice.
Kotańska M, Dziubina A, Szafarz M, Mika K, Reguła K, Bednarski M, Zygmunt M, Drabczyńska A, Sapa J, Kieć-Kononowicz K. Kotańska M, et al. Among authors: szafarz m. PLoS One. 2020 Jun 18;15(6):e0229806. doi: 10.1371/journal.pone.0229806. eCollection 2020. PLoS One. 2020. PMID: 32555600 Free PMC article.
The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling.
Sałaciak K, Głuch-Lutwin M, Siwek A, Szafarz M, Kazek G, Bednarski M, Nowiński L, Mitchell E, Jastrzębska-Więsek M, Partyka A, Wesołowska A, Kołaczkowski M, Szkaradek N, Marona H, Sapa J, Pytka K. Sałaciak K, et al. Among authors: szafarz m. J Psychopharmacol. 2020 Dec;34(12):1431-1442. doi: 10.1177/0269881120959605. Epub 2020 Oct 24. J Psychopharmacol. 2020. PMID: 33103555
42 results