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MLH1 deficiency leads to deregulated mitochondrial metabolism.
Rashid S, Freitas MO, Cucchi D, Bridge G, Yao Z, Gay L, Williams M, Wang J, Suraweera N, Silver A, McDonald SAC, Chelala C, Szabadkai G, Martin SA. Rashid S, et al. Among authors: szabadkai g. Cell Death Dis. 2019 Oct 22;10(11):795. doi: 10.1038/s41419-019-2018-y. Cell Death Dis. 2019. PMID: 31641109 Free PMC article.
PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations.
Yao Z, Jones AW, Fassone E, Sweeney MG, Lebiedzinska M, Suski JM, Wieckowski MR, Tajeddine N, Hargreaves IP, Yasukawa T, Tufo G, Brenner C, Kroemer G, Rahman S, Szabadkai G. Yao Z, et al. Among authors: szabadkai g. Oncogene. 2013 May 16;32(20):2592-600. doi: 10.1038/onc.2012.259. Epub 2012 Jul 9. Oncogene. 2013. PMID: 22777349
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
Xu R, Jones W, Wilcz-Villega E, Costa AS, Rajeeve V, Bentham RB, Bryson K, Nagano A, Yaman B, Olendo Barasa S, Wang Y, Chelala C, Cutillas P, Szabadkai G, Frezza C, Bianchi K. Xu R, et al. Among authors: szabadkai g. EMBO Rep. 2020 Sep 3;21(9):e48260. doi: 10.15252/embr.201948260. Epub 2020 Aug 11. EMBO Rep. 2020. PMID: 32783398 Free PMC article.
Mitochondria mediated cell death in diabetes.
Szabadkai G, Duchen MR. Szabadkai G, et al. Apoptosis. 2009 Dec;14(12):1405-23. doi: 10.1007/s10495-009-0363-5. Apoptosis. 2009. PMID: 19466549 Review.
Mitochondrial single-stranded DNA binding protein is required for maintenance of mitochondrial DNA and 7S DNA but is not required for mitochondrial nucleoid organisation.
Ruhanen H, Borrie S, Szabadkai G, Tyynismaa H, Jones AW, Kang D, Taanman JW, Yasukawa T. Ruhanen H, et al. Among authors: szabadkai g. Biochim Biophys Acta. 2010 Aug;1803(8):931-9. doi: 10.1016/j.bbamcr.2010.04.008. Epub 2010 Apr 28. Biochim Biophys Acta. 2010. PMID: 20434493 Free article.
No evidence for a local renin-angiotensin system in liver mitochondria.
Astin R, Bentham R, Djafarzadeh S, Horscroft JA, Kuc RE, Leung PS, Skipworth JR, Vicencio JM, Davenport AP, Murray AJ, Takala J, Jakob SM, Montgomery H, Szabadkai G. Astin R, et al. Among authors: szabadkai g. Sci Rep. 2013;3:2467. doi: 10.1038/srep02467. Sci Rep. 2013. PMID: 23959064 Free PMC article.
113 results