Szabó PT - Search Results

1

Unshielding Multidrug Resistant Cancer through Selective Iron Depletion of P-Glycoprotein-Expressing Cells.

Cserepes M, Türk D, Tóth S, Pape VFS, Gaál A, Gera M, Szabó JE, Kucsma N, Várady G, Vértessy BG, Streli C, Szabó PT, Tovari J, Szoboszlai N, Szakács G. Cserepes M, et al. Among authors: szabo pt, szabo je. Cancer Res. 2020 Feb 15;80(4):663-674. doi: 10.1158/0008-5472.CAN-19-1407. Epub 2019 Dec 30. Cancer Res. 2020. PMID: 31888888

2

Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.

Kovári J, Barabás O, Takács E, Békési A, Dubrovay Z, Pongrácz V, Zagyva I, Imre T, Szabó P, Vértessy BG. Kovári J, et al. J Biol Chem. 2004 Apr 23;279(17):17932-44. doi: 10.1074/jbc.M313643200. Epub 2004 Jan 14. J Biol Chem. 2004. PMID: 14724274 Free article.

3

Mechanistic studies of dUTPases.

Kovári J, Imre T, Szabó P, Vértessy BG. Kovári J, et al. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1475-9. doi: 10.1081/NCN-200027694. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571280

4

Synthesis and characterization of the anticancer and metal binding properties of novel pyrimidinylhydrazone derivatives.

Pape VF, Türk D, Szabó P, Wiese M, Enyedy EA, Szakács G. Pape VF, et al. J Inorg Biochem. 2015 Mar;144:18-30. doi: 10.1016/j.jinorgbio.2014.12.015. Epub 2014 Dec 20. J Inorg Biochem. 2015. PMID: 25589012 Free article.

5

Design, synthesis and biological evaluation of thiosemicarbazones, hydrazinobenzothiazoles and arylhydrazones as anticancer agents with a potential to overcome multidrug resistance.

Pape VF, Tóth S, Füredi A, Szebényi K, Lovrics A, Szabó P, Wiese M, Szakács G. Pape VF, et al. Eur J Med Chem. 2016 Jul 19;117:335-54. doi: 10.1016/j.ejmech.2016.03.078. Epub 2016 Mar 30. Eur J Med Chem. 2016. PMID: 27161177

6

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression.

Englinger B, Lötsch D, Pirker C, Mohr T, van Schoonhoven S, Boidol B, Lardeau CH, Spitzwieser M, Szabó P, Heffeter P, Lang I, Cichna-Markl M, Grasl-Kraupp B, Marian B, Grusch M, Kubicek S, Szakács G, Berger W. Englinger B, et al. Oncotarget. 2016 Aug 2;7(31):50161-50179. doi: 10.18632/oncotarget.10324. Oncotarget. 2016. PMID: 27367030 Free PMC article.

7

Pegylated liposomal formulation of doxorubicin overcomes drug resistance in a genetically engineered mouse model of breast cancer.

Füredi A, Szebényi K, Tóth S, Cserepes M, Hámori L, Nagy V, Karai E, Vajdovich P, Imre T, Szabó P, Szüts D, Tóvári J, Szakács G. Füredi A, et al. J Control Release. 2017 Sep 10;261:287-296. doi: 10.1016/j.jconrel.2017.07.010. Epub 2017 Jul 9. J Control Release. 2017. PMID: 28700899

8

Ivermectin interacts with human ABCG2.

Jani M, Makai I, Kis E, Szabó P, Nagy T, Krajcsi P, Lespine A. Jani M, et al. J Pharm Sci. 2011 Jan;100(1):94-7. doi: 10.1002/jps.22262. Epub 2010 Jun 22. J Pharm Sci. 2011. PMID: 20574995

9

Synthesis and pharmacological investigation of new N-hydroxyalkyl-2-aminophenothiazines exhibiting marked MDR inhibitory effect.

Takács D, Egyed O, Drahos L, Szabó P, Jemnitz K, Szabó M, Veres Z, Visy J, Molnár J, Riedl Z, Hajós G. Takács D, et al. Bioorg Med Chem. 2013 Jul 1;21(13):3760-79. doi: 10.1016/j.bmc.2013.04.034. Epub 2013 Apr 23. Bioorg Med Chem. 2013. PMID: 23673221 Free article.

10

Modulation of nose-to-brain delivery of a P-glycoprotein (MDR1) substrate model drug (quinidine) in rats.

Bors LA, Bajza Á, Mándoki M, Tasi BJ, Cserey G, Imre T, Szabó P, Erdő F. Bors LA, et al. Brain Res Bull. 2020 Jul;160:65-73. doi: 10.1016/j.brainresbull.2020.04.012. Epub 2020 Apr 26. Brain Res Bull. 2020. PMID: 32344126 Free article.

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