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Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux.
Luethi D, Maier J, Rudin D, Szöllősi D, Angenoorth TJF, Stankovic S, Schittmayer M, Burger I, Yang JW, Jaentsch K, Holy M, Das AK, Brameshuber M, Camacho-Hernandez GA, Casiraghi A, Newman AH, Kudlacek O, Birner-Gruenberger R, Stockner T, Schütz GJ, Sitte HH. Luethi D, et al. Among authors: szollosi d. Commun Biol. 2022 Nov 17;5(1):1259. doi: 10.1038/s42003-022-04210-1. Commun Biol. 2022. PMID: 36396757 Free PMC article.
Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.
Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman AS, Lukacs GL. Veit G, et al. Among authors: szollosi d. Sci Transl Med. 2014 Jul 23;6(246):246ra97. doi: 10.1126/scitranslmed.3008889. Sci Transl Med. 2014. PMID: 25101887 Free PMC article.
Comparison of mechanistic transport cycle models of ABC exporters.
Szöllősi D, Rose-Sperling D, Hellmich UA, Stockner T. Szöllősi D, et al. Biochim Biophys Acta Biomembr. 2018 Apr;1860(4):818-832. doi: 10.1016/j.bbamem.2017.10.028. Epub 2017 Oct 31. Biochim Biophys Acta Biomembr. 2018. PMID: 29097275 Free PMC article. Review.
105 results