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Page 1
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection.
Dowell AC, Butler MS, Jinks E, Tut G, Lancaster T, Sylla P, Begum J, Bruton R, Pearce H, Verma K, Logan N, Tyson G, Spalkova E, Margielewska-Davies S, Taylor GS, Syrimi E, Baawuah F, Beckmann J, Okike IO, Ahmad S, Garstang J, Brent AJ, Brent B, Ireland G, Aiano F, Amin-Chowdhury Z, Jones S, Borrow R, Linley E, Wright J, Azad R, Waiblinger D, Davis C, Thomson EC, Palmarini M, Willett BJ, Barclay WS, Poh J, Amirthalingam G, Brown KE, Ramsay ME, Zuo J, Moss P, Ladhani S. Dowell AC, et al. Among authors: syrimi e. Nat Immunol. 2022 Jan;23(1):40-49. doi: 10.1038/s41590-021-01089-8. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937928 Free PMC article.
SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.
Perez-Toledo M, Faustini SE, Jossi SE, Shields AM, Marcial-Juarez E, Kanthimathinathan HK, Allen JD, Watanabe Y, Goodall M, Willcox BE, Willcox CR, Salim M, Wraith DC, Veenith TV, Syrimi E, Drayson MT, Jyothish D, Al-Abadi E, Chikermane A, Welch SB, Masilamani K, Hackett S, Crispin M, Scholefield BR, Cunningham AF, Richter AG. Perez-Toledo M, et al. Among authors: syrimi e. Pediatr Allergy Immunol. 2021 Jul;32(5):1125-1129. doi: 10.1111/pai.13504. Epub 2021 Apr 18. Pediatr Allergy Immunol. 2021. PMID: 33724541 Free PMC article. No abstract available.
The immune landscape of SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Children (MIS-C) from acute disease to recovery.
Syrimi E, Fennell E, Richter A, Vrljicak P, Stark R, Ott S, Murray PG, Al-Abadi E, Chikermane A, Dawson P, Hackett S, Jyothish D, Kanthimathinathan HK, Monaghan S, Nagakumar P, Scholefield BR, Welch S, Khan N, Faustini S, Davies K, Zelek WM, Kearns P, Taylor GS. Syrimi E, et al. iScience. 2021 Nov 19;24(11):103215. doi: 10.1016/j.isci.2021.103215. Epub 2021 Oct 2. iScience. 2021. PMID: 34632327 Free PMC article.
Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program.
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. McMurray JL, et al. Among authors: syrimi e. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. Cell Rep. 2022. PMID: 35613583 Free PMC article.
Enhanced CD95 and interleukin 18 signalling accompany T cell receptor Vβ21.3+ activation in multi-inflammatory syndrome in children.
Zhang Z, Kean IRL, Dratva LM, Clark JA, Syrimi E, Khan N, Daubney E, White D, O'Neill L, Chisholm C, Payne C, Benkenstein S, Kupiec K, Galassini R, Wright V, Winmill H, Robbins C, Brown K, Ramnarayan P, Scholefield B, Peters M, Klein N, Montgomery H, Meyer KB, Teichmann SA, Bryant C, Taylor G, Pathan N. Zhang Z, et al. Among authors: syrimi e. Nat Commun. 2024 May 18;15(1):4227. doi: 10.1038/s41467-024-48699-y. Nat Commun. 2024. PMID: 38762592 Free PMC article.
What are CAR T-cells?
Syrimi E, Bailey S. Syrimi E, et al. Arch Dis Child Educ Pract Ed. 2024 Mar 6:edpract-2023-326081. doi: 10.1136/archdischild-2023-326081. Online ahead of print. Arch Dis Child Educ Pract Ed. 2024. PMID: 38448217 No abstract available.