Symons A - Search Results

1

STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets.

Bhatt D, Kang B, Sawant D, Zheng L, Perez K, Huang Z, Sekirov L, Wolak D, Huang JY, Liu X, DeVoss J, Manzanillo PS, Pierce N, Zhang Z, Symons A, Ouyang W. Bhatt D, et al. Among authors: symons a. J Exp Med. 2021 Jun 7;218(6):e20201329. doi: 10.1084/jem.20201329. J Exp Med. 2021. PMID: 33900375 Free PMC article.

2

Dual Mechanisms for Balancing Th17 and Treg Cell Fate by CREB.

Symons A, Ouyang W. Symons A, et al. EBioMedicine. 2017 Nov;25:20-21. doi: 10.1016/j.ebiom.2017.10.031. Epub 2017 Nov 10. EBioMedicine. 2017. PMID: 29129697 Free PMC article.

3

Are Th17 cells in the gut pathogenic or protective?

Symons A, Budelsky AL, Towne JE. Symons A, et al. Mucosal Immunol. 2012 Jan;5(1):4-6. doi: 10.1038/mi.2011.51. Epub 2011 Nov 9. Mucosal Immunol. 2012. PMID: 22071661 Free article.

4

High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms.

Jin HY, Tudor Y, Choi K, Shao Z, Sparling BA, McGivern JG, Symons A. Jin HY, et al. Among authors: symons a. SLAS Discov. 2020 Feb;25(2):215-222. doi: 10.1177/2472555219893277. Epub 2019 Dec 18. SLAS Discov. 2020. PMID: 31849250 Free article.

5

Discovery of 6-Oxo-4-phenyl-hexanoic acid derivatives as RORγt inverse agonists showing favorable ADME profile.

Nakajima R, Oono H, Kumazawa K, Ida T, Hirata J, White RD, Min X, Guzman-Perez A, Wang Z, Symons A, Singh SK, Mothe SR, Belyakov S, Chakrabarti A, Shuto S. Nakajima R, et al. Among authors: symons a. Bioorg Med Chem Lett. 2021 Mar 15;36:127786. doi: 10.1016/j.bmcl.2021.127786. Epub 2021 Jan 23. Bioorg Med Chem Lett. 2021. PMID: 33493627

6

Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

Maxwell JR, Zhang Y, Brown WA, Smith CL, Byrne FR, Fiorino M, Stevens E, Bigler J, Davis JA, Rottman JB, Budelsky AL, Symons A, Towne JE. Maxwell JR, et al. Among authors: symons a. Immunity. 2015 Oct 20;43(4):739-50. doi: 10.1016/j.immuni.2015.08.019. Epub 2015 Sep 29. Immunity. 2015. PMID: 26431947 Free article.

7

Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists.

Nakajima R, Oono H, Sugiyama S, Matsueda Y, Ida T, Kakuda S, Hirata J, Baba A, Makino A, Matsuyama R, White RD, Wurz RΡ, Shin Y, Min X, Guzman-Perez A, Wang Z, Symons A, Singh SK, Mothe SR, Belyakov S, Chakrabarti A, Shuto S. Nakajima R, et al. Among authors: symons a. ACS Med Chem Lett. 2020 Feb 27;11(4):528-534. doi: 10.1021/acsmedchemlett.9b00649. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292560 Free PMC article.

8

Broad-scale pesticide screening finds anticoagulant rodenticide and legacy pesticides in Australian frogs.

Rowley JJL, Symons A, Doyle C, Hall J, Rose K, Stapp L, Lettoof DC. Rowley JJL, et al. Among authors: symons a. Sci Total Environ. 2024 Jun 20;930:172526. doi: 10.1016/j.scitotenv.2024.172526. Epub 2024 Apr 16. Sci Total Environ. 2024. PMID: 38636866 Free article.

9

Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy.

Sepah YJ, Do DV, Mesquida M, Day BM, Blotner S, Afridi R, Halim MS, Hong K, Wakshull E, Fauser S, Stoilov I, Dong Nguyen Q; HARBOR; READ-3 Investigators. Sepah YJ, et al. Eye (Lond). 2024 Apr 15. doi: 10.1038/s41433-024-03015-2. Online ahead of print. Eye (Lond). 2024. PMID: 38622330

10

A second update on mapping the human genetic architecture of COVID-19.

COVID-19 Host Genetics Initiative. COVID-19 Host Genetics Initiative. Nature. 2023 Sep;621(7977):E7-E26. doi: 10.1038/s41586-023-06355-3. Epub 2023 Sep 6. Nature. 2023. PMID: 37674002 Free PMC article. No abstract available.

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