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Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway.
Antioxidants (Basel). 2020 Dec 9;9(12):1253. doi: 10.3390/antiox9121253.
Antioxidants (Basel). 2020.
PMID: 33317056
Free PMC article.
TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells.
Syed Mortadza SA, Wang L, Li D, Jiang LH.
Syed Mortadza SA, et al.
Front Immunol. 2015 Aug 7;6:407. doi: 10.3389/fimmu.2015.00407. eCollection 2015.
Front Immunol. 2015.
PMID: 26300888
Free PMC article.
Review.
Item in Clipboard
The TRPM2 channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia.
Jiang LH, Li X, Syed Mortadza SA, Lovatt M, Yang W.
Jiang LH, et al. Among authors: syed mortadza sa.
Ageing Res Rev. 2018 Nov;47:67-79. doi: 10.1016/j.arr.2018.07.002. Epub 2018 Jul 17.
Ageing Res Rev. 2018.
PMID: 30009973
Free article.
Review.
Item in Clipboard
TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies.
Malko P, Syed Mortadza SA, McWilliam J, Jiang LH.
Malko P, et al. Among authors: syed mortadza sa.
Front Pharmacol. 2019 Mar 12;10:239. doi: 10.3389/fphar.2019.00239. eCollection 2019.
Front Pharmacol. 2019.
PMID: 30914955
Free PMC article.
Review.
Item in Clipboard
Melastatin-related transient receptor potential 2 channel in Aβ42-induced neuroinflammation: implications to Alzheimer's disease mechanism and development of therapeutics.
Wei L, Syed Mortadza SA, Jiang LH.
Wei L, et al. Among authors: syed mortadza sa.
Neural Regen Res. 2018 Mar;13(3):419-420. doi: 10.4103/1673-5374.228720.
Neural Regen Res. 2018.
PMID: 29623922
Free PMC article.
No abstract available.
Item in Clipboard
Predisposition to Alzheimer's and Age-Related Brain Pathologies by PM2.5 Exposure: Perspective on the Roles of Oxidative Stress and TRPM2 Channel.
Wang L, Wei LY, Ding R, Feng Y, Li D, Li C, Malko P, Syed Mortadza SA, Wu W, Yin Y, Jiang LH.
Wang L, et al. Among authors: syed mortadza sa.
Front Physiol. 2020 Feb 26;11:155. doi: 10.3389/fphys.2020.00155. eCollection 2020.
Front Physiol. 2020.
PMID: 32174842
Free PMC article.
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ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics.
Wei L, Syed Mortadza SA, Yan J, Zhang L, Wang L, Yin Y, Li C, Chalon S, Emond P, Belzung C, Li D, Lu C, Roger S, Jiang LH.
Wei L, et al. Among authors: syed mortadza sa.
Neurosci Biobehav Rev. 2018 Apr;87:192-205. doi: 10.1016/j.neubiorev.2018.02.005. Epub 2018 Feb 14.
Neurosci Biobehav Rev. 2018.
PMID: 29453990
Free article.
Review.
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