Sydor PK - Search Results

1

Structural basis for chain release from the enacyloxin polyketide synthase.

Kosol S, Gallo A, Griffiths D, Valentic TR, Masschelein J, Jenner M, de Los Santos ELC, Manzi L, Sydor PK, Rea D, Zhou S, Fülöp V, Oldham NJ, Tsai SC, Challis GL, Lewandowski JR. Kosol S, et al. Among authors: sydor pk. Nat Chem. 2019 Oct;11(10):913-923. doi: 10.1038/s41557-019-0335-5. Epub 2019 Sep 23. Nat Chem. 2019. PMID: 31548674 Free PMC article.

2

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis.

Masschelein J, Sydor PK, Hobson C, Howe R, Jones C, Roberts DM, Ling Yap Z, Parkhill J, Mahenthiralingam E, Challis GL. Masschelein J, et al. Among authors: sydor pk. Nat Chem. 2019 Oct;11(10):906-912. doi: 10.1038/s41557-019-0309-7. Epub 2019 Sep 23. Nat Chem. 2019. PMID: 31548673 Free PMC article.

3

Molecular basis for control of antibiotic production by a bacterial hormone.

Zhou S, Bhukya H, Malet N, Harrison PJ, Rea D, Belousoff MJ, Venugopal H, Sydor PK, Styles KM, Song L, Cryle MJ, Alkhalaf LM, Fülöp V, Challis GL, Corre C. Zhou S, et al. Among authors: sydor pk. Nature. 2021 Feb;590(7846):463-467. doi: 10.1038/s41586-021-03195-x. Epub 2021 Feb 3. Nature. 2021. PMID: 33536618

4

Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes.

Sydor PK, Barry SM, Odulate OM, Barona-Gomez F, Haynes SW, Corre C, Song L, Challis GL. Sydor PK, et al. Nat Chem. 2011 May;3(5):388-92. doi: 10.1038/nchem.1024. Epub 2011 Apr 17. Nat Chem. 2011. PMID: 21505498 Free PMC article.

5

Oxidative tailoring reactions catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example.

Sydor PK, Challis GL. Sydor PK, et al. Methods Enzymol. 2012;516:195-218. doi: 10.1016/B978-0-12-394291-3.00002-2. Methods Enzymol. 2012. PMID: 23034230 Review.

6

Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis.

Haynes SW, Sydor PK, Stanley AE, Song L, Challis GL. Haynes SW, et al. Among authors: sydor pk. Chem Commun (Camb). 2008 Apr 28;(16):1865-7. doi: 10.1039/b801677a. Epub 2008 Mar 14. Chem Commun (Camb). 2008. PMID: 18401500

7

Stereochemical elucidation of streptorubin B.

Haynes SW, Sydor PK, Corre C, Song L, Challis GL. Haynes SW, et al. Among authors: sydor pk. J Am Chem Soc. 2011 Feb 16;133(6):1793-8. doi: 10.1021/ja109164t. Epub 2010 Dec 17. J Am Chem Soc. 2011. PMID: 21166415

8

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis.

Mo S, Sydor PK, Corre C, Alhamadsheh MM, Stanley AE, Haynes SW, Song L, Reynolds KA, Challis GL. Mo S, et al. Among authors: sydor pk. Chem Biol. 2008 Feb;15(2):137-48. doi: 10.1016/j.chembiol.2007.11.015. Chem Biol. 2008. PMID: 18291318

9

Structure and function of the RedJ protein, a thioesterase from the prodiginine biosynthetic pathway in Streptomyces coelicolor.

Whicher JR, Florova G, Sydor PK, Singh R, Alhamadsheh M, Challis GL, Reynolds KA, Smith JL. Whicher JR, et al. Among authors: sydor pk. J Biol Chem. 2011 Jun 24;286(25):22558-69. doi: 10.1074/jbc.M110.213512. Epub 2011 May 3. J Biol Chem. 2011. PMID: 21543318 Free PMC article.

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