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Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: its activation coupled with G0/G1 phase cell cycle arrest.
Mohan S, Abdul AB, Abdelwahab SI, Al-Zubairi AS, Sukari MA, Abdullah R, Elhassan Taha MM, Ibrahim MY, Syam S. Mohan S, et al. Among authors: syam s. J Ethnopharmacol. 2010 Oct 5;131(3):592-600. doi: 10.1016/j.jep.2010.07.043. Epub 2010 Jul 29. J Ethnopharmacol. 2010. PMID: 20673794
Inclusion Complex of Zerumbone with Hydroxypropyl- β -Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio.
Muhammad Nadzri N, Abdul AB, Sukari MA, Abdelwahab SI, Eid EE, Mohan S, Kamalidehghan B, Anasamy T, Ng KB, Syam S, Arbab IA, Rahman HS, Ali HM. Muhammad Nadzri N, et al. Among authors: syam s. Evid Based Complement Alternat Med. 2013;2013:810632. doi: 10.1155/2013/810632. Epub 2013 May 8. Evid Based Complement Alternat Med. 2013. PMID: 23737847 Free PMC article.
The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: possible involvement of indirect antioxidant action.
Abdelwahab SI, Mohan S, Abdulla MA, Sukari MA, Abdul AB, Taha MM, Syam S, Ahmad S, Lee KH. Abdelwahab SI, et al. Among authors: syam s. J Ethnopharmacol. 2011 Sep 2;137(2):963-70. doi: 10.1016/j.jep.2011.07.010. Epub 2011 Jul 8. J Ethnopharmacol. 2011. PMID: 21771650
Synthesis of chalcones with anticancer activities.
Syam S, Abdelwahab SI, Al-Mamary MA, Mohan S. Syam S, et al. Molecules. 2012 May 25;17(6):6179-95. doi: 10.3390/molecules17066179. Molecules. 2012. PMID: 22634834 Free PMC article.
Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition.
Arbab IA, Looi CY, Abdul AB, Cheah FK, Wong WF, Sukari MA, Abdullah R, Mohan S, Syam S, Arya A, Mohamed Elhassan Taha M, Muharram B, Rais Mustafa M, Ibrahim Abdelwahab S. Arbab IA, et al. Among authors: syam s. Evid Based Complement Alternat Med. 2012;2012:856029. doi: 10.1155/2012/856029. Epub 2012 Oct 3. Evid Based Complement Alternat Med. 2012. PMID: 23091559 Free PMC article.
Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-κB signalling and G0/G1 cell cycle arrest: a bioassay-guided approach.
Arbab IA, Abdul AB, Sukari MA, Abdullah R, Syam S, Kamalidehghan B, Ibrahim MY, Taha MM, Abdelwahab SI, Ali HM, Mohan S. Arbab IA, et al. Among authors: syam s. J Ethnopharmacol. 2013 Jan 9;145(1):343-54. doi: 10.1016/j.jep.2012.11.020. Epub 2012 Nov 23. J Ethnopharmacol. 2013. PMID: 23178663
In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot).
Isa NM, Abdelwahab SI, Mohan S, Abdul AB, Sukari MA, Taha MM, Syam S, Narrima P, Cheah SCh, Ahmad S, Mustafa MR. Isa NM, et al. Among authors: syam s. Braz J Med Biol Res. 2012 Jun;45(6):524-30. doi: 10.1590/s0100-879x2012007500022. Epub 2012 Feb 25. Braz J Med Biol Res. 2012. PMID: 22358425 Free PMC article.
Involvement of NF-κB and Bcl2/Bax signaling pathways in the apoptosis of MCF7 cells induced by a xanthone compound Pyranocycloartobiloxanthone A.
Mohan S, Abdelwahab SI, Kamalidehghan B, Syam S, May KS, Harmal NS, Shafifiyaz N, Hadi AH, Hashim NM, Rahmani M, Taha MM, Cheah SC, Zajmi A. Mohan S, et al. Among authors: syam s. Phytomedicine. 2012 Aug 15;19(11):1007-15. doi: 10.1016/j.phymed.2012.05.012. Epub 2012 Jun 26. Phytomedicine. 2012. PMID: 22739412
36 results