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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: swinnen jv. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy.
Shariatzadeh M, Nagtzaam NMA, van Vark-van der Zee L, van Holten-Neelen C, Verhoeven AJM, Dehairs J, Swinnen JV, Leijten F, Ten Berge JC, Ciriano JPM, Wong KT, Mulder M, Leenen PJM, Dik WA. Shariatzadeh M, et al. Among authors: swinnen jv. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):8. doi: 10.1167/iovs.64.5.8. Invest Ophthalmol Vis Sci. 2023. PMID: 37159194 Free PMC article.
Peroxisome disruption alters lipid metabolism and potentiates antitumor response with MAPK-targeted therapy in melanoma.
Huang F, Cai F, Dahabieh MS, Gunawardena K, Talebi A, Dehairs J, El-Turk F, Park JY, Li M, Goncalves C, Gagnon N, Su J, LaPierre JH, Gaub P, Joyal JS, Mitchell JJ, Swinnen JV, Miller WH Jr, Del Rincón SV. Huang F, et al. Among authors: swinnen jv. J Clin Invest. 2023 Oct 16;133(20):e166644. doi: 10.1172/JCI166644. J Clin Invest. 2023. PMID: 37616051 Free PMC article.
Extracellular vesicle-associated cholesterol supports the regenerative functions of macrophages in the brain.
Vanherle S, Guns J, Loix M, Mingneau F, Dierckx T, Wouters F, Kuipers K, Vangansewinkel T, Wolfs E, Lins PP, Bronckaers A, Lambrichts I, Dehairs J, Swinnen JV, Verberk SGS, Haidar M, Hendriks JJA, Bogie JFJ. Vanherle S, et al. Among authors: swinnen jv. J Extracell Vesicles. 2023 Dec;12(12):e12394. doi: 10.1002/jev2.12394. J Extracell Vesicles. 2023. PMID: 38124258 Free PMC article.
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
Zhu Y, Burg T, Neyrinck K, Vervliet T, Nami F, Vervoort E, Ahuja K, Sassano ML, Chai YC, Tharkeshwar AK, De Smedt J, Hu H, Bultynck G, Agostinis P, Swinnen JV, Van Den Bosch L, da Costa RFM, Verfaillie C. Zhu Y, et al. Among authors: swinnen jv. Acta Neuropathol. 2024 Jan 3;147(1):6. doi: 10.1007/s00401-023-02666-x. Acta Neuropathol. 2024. PMID: 38170217 Free PMC article.
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells.
Prior R, Silva A, Vangansewinkel T, Idkowiak J, Tharkeshwar AK, Hellings TP, Michailidou I, Vreijling J, Loos M, Koopmans B, Vlek N, Agaser C, Kuipers TB, Michiels C, Rossaert E, Verschoren S, Vermeire W, de Laat V, Dehairs J, Eggermont K, van den Biggelaar D, Bademosi AT, Meunier FA, vandeVen M, Van Damme P, Mei H, Swinnen JV, Lambrichts I, Baas F, Fluiter K, Wolfs E, Van Den Bosch L. Prior R, et al. Among authors: swinnen jv. Brain. 2024 May 14:awae158. doi: 10.1093/brain/awae158. Online ahead of print. Brain. 2024. PMID: 38743588
ACSM1 and ACSM3 regulate fatty acid metabolism to support prostate cancer growth and constrain ferroptosis.
Shrestha RK, Nassar ZD, Hanson AR, Iggo R, Townley SL, Dehairs J, Mah CY, Helm M, Alizadeh-Ghodsi M, Pickering M, Ghesquiere B, Watt MJ, Quek LE, Hoy AJ, Tilley WD, Swinnen JV, Butler LM, Selth LA. Shrestha RK, et al. Among authors: swinnen jv. Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-1489. Online ahead of print. Cancer Res. 2024. PMID: 38657108
173 results