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Fatty acid synthesis is a therapeutic target in human liposarcoma.
Olsen AM, Eisenberg BL, Kuemmerle NB, Flanagan AJ, Morganelli PM, Lombardo PS, Swinnen JV, Kinlaw WB. Olsen AM, et al. Among authors: swinnen jv. Int J Oncol. 2010 May;36(5):1309-14. doi: 10.3892/ijo_00000616. Int J Oncol. 2010. PMID: 20372807 Free PMC article.
Lipoprotein lipase links dietary fat to solid tumor cell proliferation.
Kuemmerle NB, Rysman E, Lombardo PS, Flanagan AJ, Lipe BC, Wells WA, Pettus JR, Froehlich HM, Memoli VA, Morganelli PM, Swinnen JV, Timmerman LA, Chaychi L, Fricano CJ, Eisenberg BL, Coleman WB, Kinlaw WB. Kuemmerle NB, et al. Among authors: swinnen jv. Mol Cancer Ther. 2011 Mar;10(3):427-36. doi: 10.1158/1535-7163.MCT-10-0802. Epub 2011 Jan 31. Mol Cancer Ther. 2011. PMID: 21282354 Free PMC article.
Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles.
Marien E, Meister M, Muley T, Fieuws S, Bordel S, Derua R, Spraggins J, Van de Plas R, Dehairs J, Wouters J, Bagadi M, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Waelkens E, Swinnen JV. Marien E, et al. Among authors: swinnen jv. Int J Cancer. 2015 Oct 1;137(7):1539-48. doi: 10.1002/ijc.29517. Epub 2015 Apr 7. Int J Cancer. 2015. PMID: 25784292 Free PMC article.
p53 attenuates AKT signaling by modulating membrane phospholipid composition.
Rueda-Rincon N, Bloch K, Derua R, Vyas R, Harms A, Hankemeier T, Khan NA, Dehairs J, Bagadi M, Binda MM, Waelkens E, Marine JC, Swinnen JV. Rueda-Rincon N, et al. Among authors: swinnen jv. Oncotarget. 2015 Aug 28;6(25):21240-54. doi: 10.18632/oncotarget.4067. Oncotarget. 2015. PMID: 26061814 Free PMC article.
Lipidomics in drug development.
Dehairs J, Derua R, Rueda-Rincon N, Swinnen JV. Dehairs J, et al. Among authors: swinnen jv. Drug Discov Today Technol. 2015 Jun;13:33-8. doi: 10.1016/j.ddtec.2015.03.002. Epub 2015 May 7. Drug Discov Today Technol. 2015. PMID: 26190681 Review.
Identification of drugs that restore primary cilium expression in cancer cells.
Khan NA, Willemarck N, Talebi A, Marchand A, Binda MM, Dehairs J, Rueda-Rincon N, Daniels VW, Bagadi M, Thimiri Govinda Raj DB, Vanderhoydonc F, Munck S, Chaltin P, Swinnen JV. Khan NA, et al. Among authors: swinnen jv. Oncotarget. 2016 Mar 1;7(9):9975-92. doi: 10.18632/oncotarget.7198. Oncotarget. 2016. PMID: 26862738 Free PMC article.
Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.
Marien E, Meister M, Muley T, Gomez Del Pulgar T, Derua R, Spraggins JM, Van de Plas R, Vanderhoydonc F, Machiels J, Binda MM, Dehairs J, Willette-Brown J, Hu Y, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Lacal JC, Waelkens E, Swinnen JV. Marien E, et al. Among authors: swinnen jv. Oncotarget. 2016 Mar 15;7(11):12582-97. doi: 10.18632/oncotarget.7179. Oncotarget. 2016. PMID: 26862848 Free PMC article.
177 results