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A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques.
Zhang P, Narayanan E, Liu Q, Tsybovsky Y, Boswell K, Ding S, Hu Z, Follmann D, Lin Y, Miao H, Schmeisser H, Rogers D, Falcone S, Elbashir SM, Presnyak V, Bahl K, Prabhakaran M, Chen X, Sarfo EK, Ambrozak DR, Gautam R, Martin MA, Swerczek J, Herbert R, Weiss D, Misamore J, Ciaramella G, Himansu S, Stewart-Jones G, McDermott A, Koup RA, Mascola JR, Finzi A, Carfi A, Fauci AS, Lusso P. Zhang P, et al. Among authors: swerczek j. Nat Med. 2021 Dec;27(12):2234-2245. doi: 10.1038/s41591-021-01574-5. Epub 2021 Dec 9. Nat Med. 2021. PMID: 34887575
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus (RSV) Prefusion F Protein Is More Effective than RSV for Boosting a Primary Immunization with RSV.
Liang B, Matsuoka Y, Le Nouën C, Liu X, Herbert R, Swerczek J, Santos C, Paneru M, Collins PL, Buchholz UJ, Munir S. Liang B, et al. Among authors: swerczek j. J Virol. 2020 Dec 22;95(2):e01512-20. doi: 10.1128/JVI.01512-20. Print 2020 Dec 22. J Virol. 2020. PMID: 33115876 Free PMC article.
Improved Prefusion Stability, Optimized Codon Usage, and Augmented Virion Packaging Enhance the Immunogenicity of Respiratory Syncytial Virus Fusion Protein in a Vectored-Vaccine Candidate.
Liang B, Ngwuta JO, Surman S, Kabatova B, Liu X, Lingemann M, Liu X, Yang L, Herbert R, Swerczek J, Chen M, Moin SM, Kumar A, McLellan JS, Kwong PD, Graham BS, Collins PL, Munir S. Liang B, et al. Among authors: swerczek j. J Virol. 2017 Jul 12;91(15):e00189-17. doi: 10.1128/JVI.00189-17. Print 2017 Aug 1. J Virol. 2017. PMID: 28539444 Free PMC article.
Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector.
Liang B, Ngwuta JO, Herbert R, Swerczek J, Dorward DW, Amaro-Carambot E, Mackow N, Kabatova B, Lingemann M, Surman S, Yang L, Chen M, Moin SM, Kumar A, McLellan JS, Kwong PD, Graham BS, Schaap-Nutt A, Collins PL, Munir S. Liang B, et al. Among authors: swerczek j. J Virol. 2016 Oct 14;90(21):10022-10038. doi: 10.1128/JVI.01196-16. Print 2016 Nov 1. J Virol. 2016. PMID: 27581977 Free PMC article.
Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques.
Klatt NR, Canary LA, Vanderford TH, Vinton CL, Engram JC, Dunham RM, Cronise HE, Swerczek JM, Lafont BA, Picker LJ, Silvestri G, Brenchley JM. Klatt NR, et al. Among authors: swerczek jm. J Virol. 2012 Jan;86(2):1203-13. doi: 10.1128/JVI.06033-11. Epub 2011 Nov 16. J Virol. 2012. PMID: 22090099 Free PMC article.
Nonhuman primates exposed to Zika virus in utero are not protected against reinfection at 1 year postpartum.
Vannella KM, Stein S, Connelly M, Swerczek J, Amaro-Carambot E, Coyle EM, Babyak A, Winkler CW, Saturday G, Gai ND, Hammoud DA, Dowd KA, Valencia LP, Ramos-Benitez MJ, Kindrachuk J, Pierson TC, Peterson KE, Brenchley JM, Whitehead SS, Khurana S, Herbert R, Chertow DS. Vannella KM, et al. Among authors: swerczek j. Sci Transl Med. 2020 Oct 28;12(567):eaaz4997. doi: 10.1126/scitranslmed.aaz4997. Sci Transl Med. 2020. PMID: 33115950
Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein.
Alamares-Sapuay J, Kishko M, Lai C, Parrington M, Delagrave S, Herbert R, Castens A, Swerczek J, Luongo C, Yang L, Collins PL, Buchholz UJ, Zhang L. Alamares-Sapuay J, et al. Among authors: swerczek j. PLoS One. 2024 Apr 9;19(4):e0301773. doi: 10.1371/journal.pone.0301773. eCollection 2024. PLoS One. 2024. PMID: 38593167 Free PMC article.
Pathobiology of hepatitis E: lessons learned from primate models.
Purcell RH, Engle RE, Govindarajan S, Herbert R, St Claire M, Elkins WR, Cook A, Shaver C, Beauregard M, Swerczek J, Emerson SU. Purcell RH, et al. Among authors: swerczek j. Emerg Microbes Infect. 2013 Mar;2(3):e9. doi: 10.1038/emi.2013.9. Epub 2013 Mar 13. Emerg Microbes Infect. 2013. PMID: 26038457 Free PMC article.