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A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins.
Lu X, Chandravanshi M, Sabbasani VR, Gaikwad S, Hughitt VK, Gyabaah-Kessie N, Scroggins BT, Das S, Myint W, Clapp ME, Schwieters CD, Dyba MA, Bolhuis DL, Koscielniak JW, Andresson T, Emanuele MJ, Brown NG, Matsuo H, Chari R, Citrin DE, Mock BA, Swenson RE, Walters KJ. Lu X, et al. Among authors: swenson re. Nat Commun. 2024 Mar 20;15(1):2485. doi: 10.1038/s41467-024-46644-7. Nat Commun. 2024. PMID: 38509117 Free PMC article.
Structural Relationships to Efficacy for Prazole-Derived Antivirals.
Nyenhuis DA, Watanabe S, Bernstein R, Swenson RE, Raju N, Sabbasani VR, Mushti C, Lee DY, Carter C, Tjandra N. Nyenhuis DA, et al. Among authors: swenson re. Adv Sci (Weinh). 2024 Mar 6:e2308312. doi: 10.1002/advs.202308312. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38447164
Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1-13C]-Pyruvate.
Ettedgui J, Blackman B, Raju N, Kotler SA, Chekmenev EY, Goodson BM, Merkle H, Woodroofe CC, LeClair CA, Krishna MC, Swenson RE. Ettedgui J, et al. Among authors: swenson re. J Am Chem Soc. 2024 Jan 10;146(1):946-953. doi: 10.1021/jacs.3c11499. Epub 2023 Dec 28. J Am Chem Soc. 2024. PMID: 38154120 Free PMC article.
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Osei-Amponsa V, Chandravanshi M, Lu X, Magidson V, Das S, Andresson T, Dyba M, Sabbasani VR, Swenson RE, Fromont C, Shrestha B, Zhao Y, Clapp ME, Chari R, Walters KJ. Osei-Amponsa V, et al. Among authors: swenson re. Mol Cell. 2024 Feb 1;84(3):522-537.e8. doi: 10.1016/j.molcel.2023.11.035. Epub 2023 Dec 26. Mol Cell. 2024. PMID: 38151017
Tools and tactics to define specificity of metabolic chemical reporters.
Mukherjee MM, Bond MR, Abramowitz LK, Biesbrock D, Woodroofe CC, Kim EJ, Swenson RE, Hanover JA. Mukherjee MM, et al. Among authors: swenson re. Front Mol Biosci. 2023 Dec 7;10:1286690. doi: 10.3389/fmolb.2023.1286690. eCollection 2023. Front Mol Biosci. 2023. PMID: 38143802 Free PMC article.
Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function.
Yang ZH, Gorusupudi A, Lydic TA, Mondal AK, Sato S, Yamazaki I, Yamaguchi H, Tang J, Rojulpote KV, Lin AB, Decot H, Koch H, Brock DC, Arunkumar R, Shi ZD, Yu ZX, Pryor M, Kun JF, Swenson RE, Swaroop A, Bernstein PS, Remaley AT. Yang ZH, et al. Among authors: swenson re. iScience. 2023 Nov 7;26(12):108411. doi: 10.1016/j.isci.2023.108411. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047069 Free PMC article.
Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability.
Feng Y, Lee J, Yang L, Hilton MB, Morris K, Seaman S, Edupuganti VVSR, Hsu KS, Dower C, Yu G, So D, Bajgain P, Zhu Z, Dimitrov DS, Patel NL, Robinson CM, Difilippantonio S, Dyba M, Corbel A, Basuli F, Swenson RE, Kalen JD, Suthe SR, Hussain M, Italia JS, Souders CA, Gao L, Schnermann MJ, St Croix B. Feng Y, et al. Among authors: swenson re. Cell Rep. 2023 Dec 26;42(12):113503. doi: 10.1016/j.celrep.2023.113503. Epub 2023 Nov 28. Cell Rep. 2023. PMID: 38019654 Free PMC article.
PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer.
Torres-Ayuso P, Katerji M, Mehlich D, Lookingbill SA, Sabbasani VR, Liou H, Casillas AL, Chauhan SS, Serwa R, Rubin MR, Marusiak AA, Swenson RE, Warfel NA, Brognard J. Torres-Ayuso P, et al. Among authors: swenson re. Cell Chem Biol. 2024 Feb 15;31(2):326-337.e11. doi: 10.1016/j.chembiol.2023.10.023. Epub 2023 Nov 27. Cell Chem Biol. 2024. PMID: 38016478 Free article.
94 results