Sweasy JB - Search Results

1

Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.

Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB. Senejani AG, et al. Among authors: sweasy jb. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6632-7. doi: 10.1073/pnas.1200800109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493258 Free PMC article.

2

Characterization of DNA polymerase beta mutants with amino acid substitutions located in the C-terminal portion of the enzyme.

Sweasy JB, Yoon MS. Sweasy JB, et al. Mol Gen Genet. 1995 Jul 28;248(2):217-24. doi: 10.1007/BF02190803. Mol Gen Genet. 1995. PMID: 7651344

3

Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae.

Clairmont CA, Sweasy JB. Clairmont CA, et al. Among authors: sweasy jb. J Bacteriol. 1996 Feb;178(3):656-61. doi: 10.1128/jb.178.3.656-661.1996. J Bacteriol. 1996. PMID: 8550496 Free PMC article.

4

A genetic system to identify DNA polymerase beta mutator mutants.

Washington SL, Yoon MS, Chagovetz AM, Li SX, Clairmont CA, Preston BD, Eckert KA, Sweasy JB. Washington SL, et al. Among authors: sweasy jb. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1321-6. doi: 10.1073/pnas.94.4.1321. Proc Natl Acad Sci U S A. 1997. PMID: 9037051 Free PMC article.

5

Evidence for a role for DNA polymerase beta in mammalian meiosis.

Plug AW, Clairmont CA, Sapi E, Ashley T, Sweasy JB. Plug AW, et al. Among authors: sweasy jb. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1327-31. doi: 10.1073/pnas.94.4.1327. Proc Natl Acad Sci U S A. 1997. PMID: 9037052 Free PMC article.

6

The Pol beta-14 dominant negative rat DNA polymerase beta mutator mutant commits errors during the gap-filling step of base excision repair in Saccharomyces cerevisiae.

Clairmont CA, Sweasy JB. Clairmont CA, et al. Among authors: sweasy jb. J Bacteriol. 1998 May;180(9):2292-7. doi: 10.1128/JB.180.9.2292-2297.1998. J Bacteriol. 1998. PMID: 9573177 Free PMC article.

7

3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection.

Kosa JL, Sweasy JB. Kosa JL, et al. Among authors: sweasy jb. J Biol Chem. 1999 Feb 5;274(6):3851-8. doi: 10.1074/jbc.274.6.3851. J Biol Chem. 1999. PMID: 9920940 Free article.

8

The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells.

Clairmont CA, Narayanan L, Sun KW, Glazer PM, Sweasy JB. Clairmont CA, et al. Among authors: sweasy jb. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9580-5. doi: 10.1073/pnas.96.17.9580. Proc Natl Acad Sci U S A. 1999. PMID: 10449735 Free PMC article.

9

Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.

Maitra M, Gudzelak A Jr, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB. Maitra M, et al. Among authors: sweasy jb. J Biol Chem. 2002 Sep 20;277(38):35550-60. doi: 10.1074/jbc.M204953200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121998 Free article.

10

Fidelity mechanisms of DNA polymerase beta.

Sweasy JB. Sweasy JB. Prog Nucleic Acid Res Mol Biol. 2003;73:137-69. doi: 10.1016/s0079-6603(03)01005-5. Prog Nucleic Acid Res Mol Biol. 2003. PMID: 12882517 Review.

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