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Mechanical memory stored through epigenetic remodeling reduces cell therapeutic potential.
Biophys J. 2023 Apr 18;122(8):1428-1444. doi: 10.1016/j.bpj.2023.03.004. Epub 2023 Mar 4.
Biophys J. 2023.
PMID: 36871159
Free PMC article.
Nuclear deformation guides chromatin reorganization in cardiac development and disease.
Seelbinder B, Ghosh S, Schneider SE, Scott AK, Berman AG, Goergen CJ, Margulies KB, Bedi KC Jr, Casas E, Swearingen AR, Brumbaugh J, Calve S, Neu CP.
Seelbinder B, et al. Among authors: swearingen ar.
Nat Biomed Eng. 2021 Dec;5(12):1500-1516. doi: 10.1038/s41551-021-00823-9. Epub 2021 Dec 2.
Nat Biomed Eng. 2021.
PMID: 34857921
Free PMC article.
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Leveraging dominant-negative histone H3 K-to-M mutations to study chromatin during differentiation and development.
Serdyukova K, Swearingen AR, Coradin M, Nevo M, Tran H, Bajric E, Brumbaugh J.
Serdyukova K, et al. Among authors: swearingen ar.
Development. 2023 Nov 1;150(21):dev202169. doi: 10.1242/dev.202169. Epub 2023 Oct 17.
Development. 2023.
PMID: 37846748
Review.
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Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific.
Muehleman DL, Crocini C, Swearingen AR, Ozeroff CD, Leinwand LA.
Muehleman DL, et al. Among authors: swearingen ar.
Am J Physiol Heart Circ Physiol. 2022 May 1;322(5):H785-H797. doi: 10.1152/ajpheart.00644.2021. Epub 2022 Mar 18.
Am J Physiol Heart Circ Physiol. 2022.
PMID: 35302880
Free PMC article.
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Genome-wide binding analysis of 195 DNA binding proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation.
Smallegan MJ, Shehata S, Spradlin SF, Swearingen A, Wheeler G, Das A, Corbet G, Nebenfuehr B, Ahrens D, Tauber D, Lennon S, Choi K, Huynh T, Wieser T, Schneider K, Bradshaw M, Basken J, Lai M, Read T, Hynes-Grace M, Timmons D, Demasi J, Rinn JL.
Smallegan MJ, et al.
PLoS One. 2021 Jun 24;16(6):e0237055. doi: 10.1371/journal.pone.0237055. eCollection 2021.
PLoS One. 2021.
PMID: 34166368
Free PMC article.
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Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Chambers KT, Cooper MA, Swearingen AR, Brookheart RT, Schweitzer GG, Weinheimer CJ, Kovacs A, Koves TR, Muoio DM, McCommis KS, Finck BN.
Chambers KT, et al. Among authors: swearingen ar.
JCI Insight. 2021 May 10;6(9):e134340. doi: 10.1172/jci.insight.134340.
JCI Insight. 2021.
PMID: 33986192
Free PMC article.
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High-sucrose-induced maternal obesity disrupts ovarian function and decreases fertility in Drosophila melanogaster.
Brookheart RT, Swearingen AR, Collins CA, Cline LM, Duncan JG.
Brookheart RT, et al. Among authors: swearingen ar.
Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1255-1263. doi: 10.1016/j.bbadis.2017.03.014. Epub 2017 Mar 24.
Biochim Biophys Acta Mol Basis Dis. 2017.
PMID: 28344128
Free PMC article.
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