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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Thai LM, O'Reilly L, Reibe-Pal S, Sue N, Holliday H, Small L, Schmitz-Peiffer C, Dhenni R, Wang-Wei Tsai V, Norris N, Yau B, Zhang X, Lee K, Yan C, Shi YC, Kebede MA, Brink R, Cooney GJ, Irvine KM, Breit SN, Phan TG, Swarbrick A, Biden TJ. Thai LM, et al. Among authors: swarbrick a. iScience. 2023 Mar 22;26(4):106477. doi: 10.1016/j.isci.2023.106477. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091234 Free PMC article.
Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.
Hochgräfe F, Zhang L, O'Toole SA, Browne BC, Pinese M, Porta Cubas A, Lehrbach GM, Croucher DR, Rickwood D, Boulghourjian A, Shearer R, Nair R, Swarbrick A, Faratian D, Mullen P, Harrison DJ, Biankin AV, Sutherland RL, Raftery MJ, Daly RJ. Hochgräfe F, et al. Among authors: swarbrick a. Cancer Res. 2010 Nov 15;70(22):9391-401. doi: 10.1158/0008-5472.CAN-10-0911. Epub 2010 Sep 21. Cancer Res. 2010. PMID: 20861192
Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.
O'Toole SA, Machalek DA, Shearer RF, Millar EK, Nair R, Schofield P, McLeod D, Cooper CL, McNeil CM, McFarland A, Nguyen A, Ormandy CJ, Qiu MR, Rabinovich B, Martelotto LG, Vu D, Hannigan GE, Musgrove EA, Christ D, Sutherland RL, Watkins DN, Swarbrick A. O'Toole SA, et al. Among authors: swarbrick a. Cancer Res. 2011 Jun 1;71(11):4002-14. doi: 10.1158/0008-5472.CAN-10-3738. Cancer Res. 2011. PMID: 21632555
Therapeutic targets in triple negative breast cancer.
O'Toole SA, Beith JM, Millar EK, West R, McLean A, Cazet A, Swarbrick A, Oakes SR. O'Toole SA, et al. Among authors: swarbrick a. J Clin Pathol. 2013 Jun;66(6):530-42. doi: 10.1136/jclinpath-2012-201361. Epub 2013 Feb 22. J Clin Pathol. 2013. PMID: 23436929 Review.
122 results