Svanborg C - Search Results

1

HAMLET: functional properties and therapeutic potential.

Ho C S J, Rydström A, Trulsson M, Bålfors J, Storm P, Puthia M, Nadeem A, Svanborg C. Ho C S J, et al. Among authors: svanborg c. Future Oncol. 2012 Oct;8(10):1301-13. doi: 10.2217/fon.12.122. Future Oncol. 2012. PMID: 23130929 Review.

2

HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.

Svanborg C, Agerstam H, Aronson A, Bjerkvig R, Düringer C, Fischer W, Gustafsson L, Hallgren O, Leijonhuvud I, Linse S, Mossberg AK, Nilsson H, Pettersson J, Svensson M. Svanborg C, et al. Adv Cancer Res. 2003;88:1-29. doi: 10.1016/s0065-230x(03)88302-1. Adv Cancer Res. 2003. PMID: 12665051 Review.

3

HAMLET interacts with histones and chromatin in tumor cell nuclei.

Düringer C, Hamiche A, Gustafsson L, Kimura H, Svanborg C. Düringer C, et al. Among authors: svanborg c. J Biol Chem. 2003 Oct 24;278(43):42131-5. doi: 10.1074/jbc.M306462200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888554 Free article.

4

Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

Svensson M, Fast J, Mossberg AK, Düringer C, Gustafsson L, Hallgren O, Brooks CL, Berliner L, Linse S, Svanborg C. Svensson M, et al. Among authors: svanborg c. Protein Sci. 2003 Dec;12(12):2794-804. doi: 10.1110/ps.0231003. Protein Sci. 2003. PMID: 14627739 Free PMC article.

5

Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).

Svensson M, Mossberg AK, Pettersson J, Linse S, Svanborg C. Svensson M, et al. Among authors: svanborg c. Protein Sci. 2003 Dec;12(12):2805-14. doi: 10.1110/ps.0231103. Protein Sci. 2003. PMID: 14627740 Free PMC article.

6

Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival.

Fischer W, Gustafsson L, Mossberg AK, Gronli J, Mork S, Bjerkvig R, Svanborg C. Fischer W, et al. Among authors: svanborg c. Cancer Res. 2004 Mar 15;64(6):2105-12. doi: 10.1158/0008-5472.can-03-2661. Cancer Res. 2004. PMID: 15026350

7

Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid.

Gustafsson L, Leijonhufvud I, Aronsson A, Mossberg AK, Svanborg C. Gustafsson L, et al. Among authors: svanborg c. N Engl J Med. 2004 Jun 24;350(26):2663-72. doi: 10.1056/NEJMoa032454. N Engl J Med. 2004. PMID: 15215482 Free article. Clinical Trial.

8

HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy.

Gustafsson L, Hallgren O, Mossberg AK, Pettersson J, Fischer W, Aronsson A, Svanborg C. Gustafsson L, et al. Among authors: svanborg c. J Nutr. 2005 May;135(5):1299-303. doi: 10.1093/jn/135.5.1299. J Nutr. 2005. PMID: 15867328

9

Compact oleic acid in HAMLET.

Fast J, Mossberg AK, Nilsson H, Svanborg C, Akke M, Linse S. Fast J, et al. Among authors: svanborg c. FEBS Lett. 2005 Nov 7;579(27):6095-100. doi: 10.1016/j.febslet.2005.08.089. Epub 2005 Oct 6. FEBS Lett. 2005. PMID: 16229842 Free article.

10

HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.

Hallgren O, Gustafsson L, Irjala H, Selivanova G, Orrenius S, Svanborg C. Hallgren O, et al. Among authors: svanborg c. Apoptosis. 2006 Feb;11(2):221-33. doi: 10.1007/s10495-006-3607-7. Apoptosis. 2006. PMID: 16502260

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